Now showing items 71-75 of 75
Postnatal cytomegalovirus exposure in infants of antiretroviral-treated and untreated HIV-infected mothers.
(Infect Dis Obstet Gynecol, 2014)
HIV-1 and CMV are important pathogens transmitted via breastfeeding. Furthermore, perinatal CMV transmission may impact growth and disease progression in HIV-exposed infants. Although maternal antiretroviral therapy reduces ...
Development and implementation of a proficiency testing program for Luminex bead-based cytokine assays
(Journal of Immunological Methods, 2014-01-01)
Luminex bead array assays are widely used for rapid biomarker quantification due to the ability to measure up to 100 unique analytes in a single well of a 96-well plate. There has been, however, no comprehensive analysis ...
Tissue-specific genetic control of splicing: implications for the study of complex traits.
(PLoS Biol, 2008-12-23)
Numerous genome-wide screens for polymorphisms that influence gene expression have provided key insights into the genetic control of transcription. Despite this work, the relevance of specific polymorphisms to in vivo expression ...
Multiple HIV-1-specific IgG3 responses decline during acute HIV-1: implications for detection of incident HIV infection.
OBJECTIVE: Different HIV-1 antigen specificities appear in sequence after HIV-1 transmission and the immunoglobulin G (IgG) subclass responses to HIV antigens are distinct from each other. The initial predominant IgG subclass ...
Elucidation of hepatitis C virus transmission and early diversification by single genome sequencing.
(PLoS Pathog, 2012)
A precise molecular identification of transmitted hepatitis C virus (HCV) genomes could illuminate key aspects of transmission biology, immunopathogenesis and natural history. We used single genome sequencing of 2,922 half ...