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Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice. 

Cao, L; Fermor, B; Griffin, TM; Guilak, Farshid; Huebner, JL; Kraus, Virginia Byers; Rodriguiz, Ramona M; ... (9 authors) (Arthritis Res Ther, 2010)
INTRODUCTION: Obesity is a major risk factor for the development of osteoarthritis in both weight-bearing and nonweight-bearing joints. The mechanisms by which obesity influences the structural or symptomatic features of ...
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Contribution of cerebellar loops to action timing 

Prevosto, V; Raghavan, RT; Sommer, Marc A (Current Opinion in Behavioral Sciences, 2016-04-01)
Recent studies of sensorimotor processing have benefited from decision-making paradigms that emphasize the selection of appropriate movements. Selecting when to make those responses, or action timing, is important as well. ...
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Visual continuity across saccades is Influenced by expectations 

Abzug, Zachary Mitchell; Rao, Hrishikesh; Sommer, Marc A (Journal of Vision, 2016-02-09)
As we make saccades, the image on each retina is displaced, yet our visual perception is uninterrupted. This is commonly referred to as transsaccadic perceptual stability, but such a description is inadequate. Some visual ...
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Probabilistic inference under time pressure leads to a cortical-to-subcortical shift in decision evidence integration 

Beck, JM; Egner, Tobias; Ferrari, Silvia; Oh-Descher, H; Sommer, Marc A (NeuroImage, 2017-08-24)
Real-life decision-making often involves combining multiple probabilistic sources of information under finite time and cognitive resources. To mitigate these pressures, people “satisfice”, foregoing a full evaluation of ...
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Circuits for presaccadic visual remapping. 

Mayo, J Patrick; Rao, Hrishikesh; Sommer, Marc A (J Neurophysiol, 2016-12-01)
Saccadic eye movements rapidly displace the image of the world that is projected onto the retinas. In anticipation of each saccade, many neurons in the visual system shift their receptive fields. This presaccadic change ...
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Supplementary Eye Fields 

Abzug, Zachary Mitchell; Sommer, Marc A (Reference Module in Neuroscience and Biobehavioral Psychology, 2017)
The supplementary eye fields (SEFs) are located in dorsomedial frontal cortex and contribute to high-level control of eye movements. Recordings in the SEF reveal neural activity related to vision, saccades, and fixations, ...
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Serial decision-making in monkeys during an oculomotor task 

Abzug, Zachary Mitchell; Sommer, Marc A (Journal of Experimental Psychology: Animal Learning and Cognition, 2017-08-29)
Much of everyday behavior involves serial decision-making, in which the outcome of one choice affects another. An example is setting rules for oneself: choosing a behavioral rule guides appropriate choices in the future. ...
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Contribution of cerebellar loops to action timing 

Prevosto, V; Raghavan, RT; Sommer, Marc A (Current Opinion in Behavioral Sciences, 2016-02-04)
Recent studies of sensorimotor processing have benefited from decision-making paradigms that emphasize the selection of appropriate movements. Selecting when to make those responses, or action timing, is important as well. ...
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Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan. 

Bancroft-Wu, V; Batrachenko, A; De Bellis, MD; Langkammer, C; Li, W; Liu, C; Morey, Rajendra A; ... (11 authors) (Hum Brain Mapp, 2014-06)
As indicated by several recent studies, magnetic susceptibility of the brain is influenced mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination and iron deposition in the brain evolve ...
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Similar prevalence and magnitude of auditory-evoked and visually-evoked activity in the frontal eye fields: Implications for multisensory motor control 

Caruso, Valeria; Groh, Jennifer M; Pages, Daniel; Sommer, Marc A (Journal of Neurophysiology, 2016)
Saccadic eye movements can be elicited by more than one type of sensory stimulus. This implies substantial transformations of signals originating in different sense organs as they reach a common motor output pathway. In ...
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AuthorJarvis, Erich D (85)Sommer, Marc A (52)Sommer, MA (40)Caron, MG (25)Lefkowitz, RJ (25)Field, Greg D (20)Zhang, Guojie (20)Gilbert, M Thomas P (19)Jarvis, ED (19)Sommer, Marc A (17)... View MoreDate Issued2010 - 2020 (290)2000 - 2009 (85)1990 - 1999 (34)1980 - 1989 (20)1976 - 1979 (1)TypeJournal article (428)Book section (12)Other article (1)SubjectAnimals (232)Humans (90)Male (86)Female (69)Brain (65)Neurons (55)Macaca mulatta (50)Mice (46)Vocalization, Animal (39)Birds (36)... View MoreAffiliation of Duke Author(s)Basic Science Departments (441)Duke (441)
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