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Xenon and sevoflurane provide analgesia during labor and fetal brain protection in a perinatal rat model of hypoxia-ischemia.
(PloS one, 2012-01)
It is not possible to identify all pregnancies at risk of neonatal hypoxic-ischemic
encephalopathy (HIE). Many women use some form of analgesia during childbirth and
some anesthetic agents have been shown to be neuroprotective ...
Cell type-specific changes in retinal ganglion cell function induced by rod death and cone reorganization in rats.
(Journal of neurophysiology, 2017-07)
We have determined the impact of rod death and cone reorganization on the spatiotemporal
receptive fields (RFs) and spontaneous activity of distinct retinal ganglion cell
(RGC) types. We compared RGC function between healthy ...
Tenascin-C is an innate broad-spectrum, HIV-1-neutralizing protein in breast milk.
(Proceedings of the National Academy of Sciences of the United States of America, 2013-11)
Achieving an AIDS-free generation will require elimination of postnatal transmission
of HIV-1 while maintaining the nutritional and immunologic benefits of breastfeeding
for infants in developing regions. Maternal/infant ...
A craniofacial-specific monosynaptic circuit enables heightened affective pain.
(Nature neuroscience, 2017-12)
Humans often rank craniofacial pain as more severe than body pain. Evidence suggests
that a stimulus of the same intensity induces stronger pain in the face than in the
body. However, the underlying neural circuitry for ...
Strategic allocation of attention reduces temporally predictable stimulus conflict.
(J Cogn Neurosci, 2012-09)
Humans are able to continuously monitor environmental situations and adjust their
behavioral strategies to optimize performance. Here we investigate the behavioral
and brain adjustments that occur when conflicting stimulus ...
The dynamics of proactive and reactive cognitive control processes in the human brain.
(J Cogn Neurosci, 2014-05)
In this study, we leveraged the high temporal resolution of EEG to examine the neural
mechanisms underlying the flexible regulation of cognitive control that unfolds over
different timescales. We measured behavioral and ...
Steps to Health employee weight management randomized control trial: short-term follow-up results.
(J Occup Environ Med, 2015-02)
OBJECTIVE: To present the short-term follow-up findings of the Steps to Health study,
a randomized trial to evaluate the effectiveness of two employee weight management
programs offered within Duke University and the Health ...
Anti-inflammatory effects of progesterone in lipopolysaccharide-stimulated BV-2 microglia.
(PLoS One, 2014)
Female sex is associated with improved outcome in experimental brain injury models,
such as traumatic brain injury, ischemic stroke, and intracerebral hemorrhage. This
implies female gonadal steroids may be neuroprotective. ...
The 70-kDa heat shock cognate protein (Hsc73) gene is enhanced by ovarian hormones in the ventromedial hypothalamus.
(Proc Natl Acad Sci U S A, 1999-02-16)
Estrogen (E) and progesterone (P) orchestrate many cellular responses involved in
female reproductive physiology, including reproductive behaviors. E- and P-binding
neurons important for lordosis behavior have been located ...
Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1.
(J Virol, 2015-10)
UNLABELLED: Infants born to HIV-1-infected mothers in resource-limited areas where
replacement feeding is unsafe and impractical are repeatedly exposed to HIV-1 throughout
breastfeeding. Despite this, the majority of infants ...