Search

Now showing items 1-10 of 47

Serum N-propeptide of collagen IIA (PIIANP) as a marker of radiographic osteoarthritis burden.

Kraus, Virginia; Daghestani, Hikmat N; Jordan, Joanne M; Renner, Jordan B; Doherty, Michael; Wilson, A Gerry (PloS one, 2017-01)

Cartilage homeostasis relies on a balance of catabolism and anabolism of cartilage matrix. Our goal was to evaluate the burden of radiographic osteoarthritis and serum levels of type IIA procollagen amino terminal propeptide ...

Dietary Patterns Associated with Cognitive Function among the Older People in Underdeveloped Regions: Finding from the NCDFaC Study.

Kraus, Virginia; Yin, Zhaoxue; Chen, Jing; Zhang, Jian; Ren, Zeping; Dong, Kui; Wang, Zhuoqun; ... (14 authors) (Nutrients, 2018-04-09)

Although dietary patterns are crucial to cognitive function, associations of dietary patterns with cognitive function have not yet been fully understood. This cross-sectional study explored dietary patterns associated with ...

Chondroitin Sulfate Inhibits Monocyte Chemoattractant Protein-1 Release From 3T3-L1 Adipocytes: A New Treatment Opportunity for Obesity-Related Inflammation?

Kraus, Virginia; Stabler, Thomas V; Montell, Eulàlia; Vergés, Josep; Huebner, Janet L (Biomarker insights, 2017-01)

Monocyte chemoattractant protein-1 (MCP-1) overproduction from inflamed adipose tissue is a major contributor to obesity-related metabolic syndromes. 3T3-L1 embryonic fibroblasts were cultured and differentiated into adipocytes ...

Association between general joint hypermobility and knee, hip, and lumbar spine osteoarthritis by race: a cross-sectional study.

Goode, Adam; Kraus, Virginia; Flowers, Portia PE; Cleveland, Rebecca J; Schwartz, Todd A; Nelson, Amanda E; Hillstrom, Howard J; ... (11 authors) (Arthritis research & therapy, 2018-04-18)

BACKGROUND:Osteoarthritis (OA) prevalence differs by race. General joint hypermobility (GJH) may be associated with OA, but differences by race are not known. This community-based study examined the frequency of GJH and ...

Towards prevention of post-traumatic osteoarthritis: report from an international expert working group on considerations for the design and conduct of interventional studies following acute knee injury.

Kraus, Virginia; Watt, FE; Corp, N; Kingsbury, SR; Frobell, R; Englund, M; Felson, DT; ... (15 authors) (Osteoarthritis and cartilage, 2019-01)

OBJECTIVE:There are few guidelines for clinical trials of interventions for prevention of post-traumatic osteoarthritis (PTOA), reflecting challenges in this area. An international multi-disciplinary expert group including ...

Semi-quantitative MRI biomarkers of knee osteoarthritis progression in the FNIH biomarkers consortium cohort - Methodologic aspects and definition of change.

Kraus, Virginia; Roemer, Frank W; Guermazi, Ali; Collins, Jamie E; Losina, Elena; Nevitt, Michael C; Lynch, John A; ... (10 authors) (BMC musculoskeletal disorders, 2016-11-10)

To describe the scoring methodology and MRI assessments used to evaluate the cross-sectional features observed in cases and controls, to define change over time for different MRI features, and to report the extent of changes ...

Effect of high-intensity interval training on muscle remodeling in rheumatoid arthritis compared to prediabetes.

Bartlett, David; Kraus, Virginia; Kraus, William; Huffman, Kim; Andonian, Brian J; Huebner, Janet L; Willis, Leslie; ... (8 authors) (Arthritis research & therapy, 2018-12-27)

BACKGROUND:Sarcopenic obesity, associated with greater risk of cardiovascular disease (CVD) and mortality in rheumatoid arthritis (RA), may be related to dysregulated muscle remodeling. To determine whether exercise training ...

Monosodium urate crystal induced macrophage inflammation is attenuated by chondroitin sulphate: pre-clinical model for gout prophylaxis?

Kraus, Virginia; Orlowsky, Eric W; Stabler, Thomas V; Montell, Eulàlia; Vergés, Josep (BMC musculoskeletal disorders, 2014-09-27)

Chondroitin Sulphate (CS), a natural glycosaminoglycan of the extracellular matrix, has clinical benefit in symptomatic osteoarthritis but has never been tested in gout. In vitro, CS has anti-inflammatory and positive effects ...

Effects of a Single Intra-Articular Injection of a Microsphere Formulation of Triamcinolone Acetonide on Knee Osteoarthritis Pain: A Double-Blinded, Randomized, Placebo-Controlled, Multinational Study.

Kraus, Virginia; Conaghan, Philip G; Hunter, David J; Cohen, Stanley B; Berenbaum, Francis; Lieberman, Jay R; Jones, Deryk G; ... (14 authors) (The Journal of bone and joint surgery. American volume, 2018-04)

Intra-articular corticosteroids relieve osteoarthritis pain, but rapid systemic absorption limits efficacy. FX006, a novel, microsphere-based, extended-release triamcinolone acetonide (TA) formulation, prolongs TA joint ...

Select Biomarkers on the Day of Anterior Cruciate Ligament Reconstruction Predict Poor Patient-Reported Outcomes at 2-Year Follow-Up: A Pilot Study.

Kraus, Virginia; Reinke, Emily; Lattermann, Christian; Conley, Caitlin E-W; Johnson, Darren L; Huston, Laura J; Huebner, Janet L; ... (10 authors) (BioMed research international, 2018-01)

Background:The majority of patients develop posttraumatic osteoarthritis within 15 years of anterior cruciate ligament (ACL) injury. Inflammatory and chondrodegenerative biomarkers have been associated with both pain and ...

1
2
3
4
. . .
5