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    Serum N-propeptide of collagen IIA (PIIANP) as a marker of radiographic osteoarthritis burden. 

    Kraus, Virginia; Daghestani, Hikmat N; Jordan, Joanne M; Renner, Jordan B; Doherty, Michael; Wilson, A Gerry (PloS one, 2017-01)
    Cartilage homeostasis relies on a balance of catabolism and anabolism of cartilage matrix. Our goal was to evaluate the burden of radiographic osteoarthritis and serum levels of type IIA procollagen amino terminal propeptide ...
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    Association between general joint hypermobility and knee, hip, and lumbar spine osteoarthritis by race: a cross-sectional study. 

    Goode, Adam; Kraus, Virginia; Flowers, Portia PE; Cleveland, Rebecca J; Schwartz, Todd A; Nelson, Amanda E; Hillstrom, Howard J; ... (11 authors) (Arthritis research & therapy, 2018-04-18)
    BACKGROUND:Osteoarthritis (OA) prevalence differs by race. General joint hypermobility (GJH) may be associated with OA, but differences by race are not known. This community-based study examined the frequency of GJH and ...
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    Elucidating the Molecular Composition of Cartilage by Proteomics. 

    Hsueh, MF; Khabut, A; Kjellström, S; Kraus, Virginia Byers; Önnerfjord, P (J Proteome Res, 2016-02-05)
    Articular cartilage consists of chondrocytes and two major components, a collagen-rich framework and highly abundant proteoglycans. Most prior studies defining the zonal distribution of cartilage have extracted proteins ...
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    A flexible statistical model for alignment of label-free proteomics data--incorporating ion mobility and product ion information. 

    Benjamin, Ashlee M; Geromanos, SJ; Henao, R; Kraus, Virginia Byers; Lucas, Joseph E; Moseley, Martin Arthur III; Soderblom, Erik James; ... (8 authors) (BMC Bioinformatics, 2013-12-16)
    BACKGROUND: The goal of many proteomics experiments is to determine the abundance of proteins in biological samples, and the variation thereof in various physiological conditions. High-throughput quantitative proteomics, ...
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    Quantification of the whole-body burden of radiographic osteoarthritis using factor analysis. 

    Conaghan, PG; DeVellis, RF; Jordan, JM; Kraus, Virginia Byers; Nelson, AE; Renner, JB; Schwartz, TA (Arthritis Res Ther, 2011)
    INTRODUCTION: Although osteoarthritis (OA) commonly involves multiple joints, no widely accepted method for quantifying whole-body OA burden exists. Therefore, our aim was to apply factor analytic methods to radiographic ...
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    First qualification study of serum biomarkers as indicators of total body burden of osteoarthritis. 

    Jordan, J; Kepler, TB; Kraus, Virginia Byers; Renner, J; Stabler, Thomas (PLoS One, 2010-03-17)
    BACKGROUND: Osteoarthritis (OA) is a debilitating chronic multijoint disease of global proportions. OA presence and severity is usually documented by x-ray imaging but whole body imaging is impractical due to radiation exposure, ...
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    Biomarkers and proteomic analysis of osteoarthritis. 

    Hsueh, MF; Kraus, Virginia Byers; Önnerfjord, P (Matrix Biol, 2014-10)
    Our friend and colleague, Dr. Dick Heinegård, contributed greatly to the understanding of joint tissue biochemistry, the discovery and validation of arthritis-related biomarkers and the establishment of methodology for proteomic ...
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    Xanthine oxidase injurious response in acute joint injury 

    Hsueh, M-F; Kraus, Virginia Byers; Stabler, Thomas; Zura, Robert Douglas (CLINICA CHIMICA ACTA, 2015-12-07)
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    Biomarkers and proteomic analysis of osteoarthritis 

    Hsueh, M-F; Kraus, Virginia Byers; Oennerfjord, P (MATRIX BIOLOGY, 2014-10)
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    In vivo luminescence imaging of NF-κB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis. 

    Bell, RD; Bowles, RD; Huebner, JL; Kraus, Virginia Byers; Mata, BA; Mwangi, TK; Setton, Lori A (Arthritis Rheumatol, 2014-03)
    OBJECTIVE: To investigate the relationship between NF-κB activity, cytokine levels, and pain sensitivities in a rodent model of osteoarthritis (OA). METHODS: OA was induced in transgenic NF-κB-luciferase reporter mice via ...
     

     

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    Author
    Kraus, Virginia Byers (8)
    Hsueh, M-F (2)Hsueh, MF (2)Jordan, Joanne M (2)
    Kraus, Virginia (2)
    Renner, Jordan B (2)Stabler, Thomas (2)Önnerfjord, P (2)Bell, RD (1)Benjamin, Ashlee M (1)... View MoreDate Issued2014 (3)2010 (1)2011 (1)2013 (1)2015 (1)2016 (1)2017 (1)2018 (1)TypeJournal article (9)Other article (1)Subject
    Osteoarthritis (10)
    Humans (6)Proteomics (4)Biomarkers (3)Chondrocytes (3)Female (3)Male (3)Aged (2)Animals (2)Arthrography (2)... View MoreAffiliation of Duke Author(s)Clinical Science Departments (10)Duke (10)Duke Molecular Physiology Institute (10)Institutes and Centers (10)
    Medicine (10)
    Medicine, Rheumatology and Immunology (10)
    Orthopaedics (10)Pathology (10)School of Medicine (10)Basic Science Departments (3)... View More