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Hypertension and obesity as cardiovascular risk factors among HIV seropositive patients in Western Kenya.
(PLoS One, 2011)
BACKGROUND: There is increased risk of cardiovascular disease among HIV seropositive
individuals. The prevalence of HIV is highest in sub-Saharan Africa; however, HIV-related
cardiovascular risk research is largely derived ...
Clinical characteristics and 12-month outcomes of patients with valvular and non-valvular atrial fibrillation in Kenya.
(PLoS One, 2017)
BACKGROUND: Atrial fibrillation (AF) is a major contributor to the global cardiovascular
disease burden. The clinical profile and outcomes of AF patients with valvular heart
diseases in sub-Saharan Africa (SSA) have not ...
A prospective comparison of a noninvasive cardiac output monitor versus esophageal Doppler monitor for goal-directed fluid therapy in colorectal surgery patients.
(Anesth Analg, 2014-05)
BACKGROUND: Goal-directed fluid therapy (GDFT) is associated with improved outcomes
after surgery. The esophageal Doppler monitor (EDM) is widely used, but has several
limitations. The NICOM, a completely noninvasive cardiac ...
Study protocol: home-based telehealth stroke care: a randomized trial for veterans.
(Trials, 2010-06-30)
BACKGROUND: Stroke is one of the most disabling and costly impairments of adulthood
in the United States. Stroke patients clearly benefit from intensive inpatient care,
but due to the high cost, there is considerable interest ...
Differential prevalence and geographic distribution of hepatitis C virus genotypes in acute and chronic hepatitis C patients in Vietnam.
(PloS one, 2019-01)
BACKGROUND:The highest burden of disease from hepatitis C virus (HCV) is found in
Southeast Asia, but our understanding of the epidemiology of infection in many heavily
burdened countries is still limited. In particular, ...
Comparative effectiveness studies to improve clinical outcomes in end stage renal disease: the DEcIDE patient outcomes in end stage renal disease study.
(BMC Nephrol, 2012-12-06)
BACKGROUND: Evidence is lacking to inform providers' and patients' decisions about
many common treatment strategies for patients with end stage renal disease (ESRD).
METHODS/DESIGN: The DEcIDE Patient Outcomes in ESRD Study ...
Rationale and Design of the Lung Cancer Screening Implementation. Evaluation of Patient-Centered Care Study.
(Annals of the American Thoracic Society, 2017-10)
Screening for lung cancer using low-dose computed tomography has been demonstrated
to reduce lung cancer-related mortality and is being widely implemented. Further research
in this area is needed to assess the impact of ...
Simplified Predictive Instrument to Rule Out Acute Coronary Syndromes in a High-Risk Population.
(J Am Heart Assoc, 2015-12-14)
BACKGROUND: It is unclear whether diagnostic protocols based on cardiac markers to
identify low-risk chest pain patients suitable for early release from the emergency
department can be applied to patients older than 65 years ...
Safety and efficacy of ledipasvir-sofosbuvir in black patients with hepatitis C virus infection: A retrospective analysis of phase 3 data.
(Hepatology, 2016-02)
UNLABELLED: Black patients chronically infected with genotype 1 hepatitis C virus
(HCV) have historically had lower rates of response to interferon-based treatment
than patients of other races. In the phase 3 ION program, ...
Potential Cost-effectiveness of Early Identification of Hospital-acquired Infection in Critically Ill Patients.
(Ann Am Thorac Soc, 2016-03)
RATIONALE: Limitations in methods for the rapid diagnosis of hospital-acquired infections
often delay initiation of effective antimicrobial therapy. New diagnostic approaches
offer potential clinical and cost-related improvements ...