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Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice.
(Arthritis Res Ther, 2010)
INTRODUCTION: Obesity is a major risk factor for the development of osteoarthritis
in both weight-bearing and nonweight-bearing joints. The mechanisms by which obesity
influences the structural or symptomatic features of ...
A pilot randomized controlled trial with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom era veterans.
(Psychiatry Res, 2013-04-30)
Subthreshold posttraumatic stress disorder (PTSD) is associated with increased risk
for suicidality, depression, and functional impairment. We thus conducted a small
(N=12) pilot randomized controlled trial (RCT) with paroxetine ...
Effects of chronic mild traumatic brain injury on white matter integrity in iraq and afghanistan war veterans
(Human Brain Mapping, 2013-11-01)
Mild traumatic brain injury (TBI) is a common source of morbidity from the wars in
Iraq and Afghanistan. With no overt lesions on structural MRI, diagnosis of chronic
mild TBI in military veterans relies on obtaining an ...
Multifactorial determinants of the neurocognitive effects of electroconvulsive therapy.
(J ECT, 2014-06)
For many patients with neuropsychiatric illnesses, standard psychiatric treatments
with mono or combination pharmacotherapy, psychotherapy, and transcranial magnetic
stimulation are ineffective. For these patients ...
Implementation and randomized controlled trial evaluation of universal postnatal nurse home visiting.
(Am J Public Health, 2014-02)
OBJECTIVES: We evaluated whether a brief, universal, postnatal nurse home-visiting
intervention can be implemented with high penetration and fidelity, prevent emergency
health care services, and promote positive parenting ...
Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
(Hum Brain Mapp, 2014-06)
As indicated by several recent studies, magnetic susceptibility of the brain is influenced
mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination
and iron deposition in the brain evolve ...
Amygdala-prefrontal cortex functional connectivity during threat-induced anxiety and goal distraction.
(Biol Psychiatry, 2015-02-15)
BACKGROUND: Anxiety produced by environmental threats can impair goal-directed processing
and is associated with a range of psychiatric disorders, particularly when aversive
events occur unpredictably. The prefrontal cortex ...
Changes in Brain Resting-state Functional Connectivity Associated with Peripheral Nerve Block: A Pilot Study.
(Anesthesiology, 2016-08)
BACKGROUND: Limited information exists on the effects of temporary functional deafferentation
(TFD) on brain activity after peripheral nerve block (PNB) in healthy humans. Increasingly,
resting-state functional connectivity ...
The steady-state visual evoked potential in vision research: A review.
(J Vis, 2015)
Periodic visual stimulation and analysis of the resulting steady-state visual evoked
potentials were first introduced over 80 years ago as a means to study visual sensation
and perception. From the first single-channel recording ...
White matter compromise in veterans exposed to primary blast forces
(Journal of Head Trauma Rehabilitation, 2015)
OBJECTIVE:: Use diffusion tensor imaging to investigate white matter alterations associated
with blast exposure with or without acute symptoms of traumatic brain injury (TBI).
PARTICIPANTS:: Forty-five veterans of the recent ...