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Sinus Node Dysfunction Is Associated With Higher Symptom Burden and Increased Comorbid Illness: Results From the ORBIT-AF Registry.

Chang, P; Fonarow, GC; Freeman, J; Gersh, Bernard John; Go, AS; Jackson, Larry Ronald II; Kim, SH; ... (14 authors) (Clin Cardiol, 2016-02)

BACKGROUND: Patients with sinus node dysfunction (SND) have increased risk of atrial tachyarrhythmias, including atrial fibrillation (AF). To date, treatment patterns and outcomes of patients with SND and AF have not been ...

Provider specialty and atrial fibrillation treatment strategies in United States community practice: findings from the ORBIT-AF registry.

Fosbøl, Emil; Gersh, Bernard John; Holmes, DaJuanicia; Kowey, Peter R; Mahaffey, Kenneth William; Mills, RM; ORBIT-AF Investigators and Patients; ... (11 authors) (J Am Heart Assoc, 2013-07-18)

BACKGROUND: The prevalence of atrial fibrillation (AF) continues to increase; however, there are limited data describing the division of care among practitioners in the community and whether care differs depending on provider ...

Use and outcomes associated with bridging during anticoagulation interruptions in patients with atrial fibrillation: findings from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF).

Ansell, J; Chang, P; Fonarow, GC; Gersh, Bernard John; Kim, S; Kowey, Peter R; Mahaffey, Kenneth William; ... (13 authors) (Circulation, 2015-02-03)

BACKGROUND: Temporary interruption of oral anticoagulation for procedures is often required, and some propose using bridging anticoagulation. However, the use and outcomes of bridging during oral anticoagulation interruptions ...

Catheter Ablation of Atrial Fibrillation in U.S. Community Practice--Results From Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF).

Chang, P; Gersh, Bernard John; Holmqvist, Fredrik Nils; Hong, SJ; Kowey, Peter R; Naccarelli, GV; ORBIT-AF Investigators; ... (12 authors) (J Am Heart Assoc, 2015-05-21)

BACKGROUND: The characteristics of patients undergoing atrial fibrillation (AF) ablation and subsequent outcomes in community practice are not well described. METHODS AND RESULTS: Using the Outcomes Registry for Better Informed ...

Outcomes According to Cardiac Catheterization Referral and Clopidogrel Use Among Medicare Patients With Non-ST-Segment Elevation Myocardial Infarction Discharged Without In-hospital Revascularization.

Hess, Connie Ng; Hellkamp, Anne; Roe, Matthew Todd; Thomas, Laine Elliott; Scirica, BM; Peng, SA; Peterson, Eric David; ... (8 authors) (J Am Heart Assoc, 2016-03-14)

BACKGROUND: While use of P2Y12 receptor inhibitor is recommended by guidelines, few studies have examined its effectiveness among older non-ST-segment elevation myocardial infarction patients who did not undergo coronary ...

Perception Versus Actual Performance in Timely Tissue Plasminogen Activation Administration in the Management of Acute Ischemic Stroke.

Britz, GW; Constable, M; Cox, M; Fonarow, GC; Lin, CB; Olson, DaiWai M; Peterson, Eric David; ... (9 authors) (J Am Heart Assoc, 2015-07-22)

BACKGROUND: Timely thrombolytic therapy can improve stroke outcomes. Nevertheless, the ability of US hospitals to meet guidelines for intravenous tissue plasminogen activator (tPA) remains suboptimal. What is unclear is ...

Early adoption of dabigatran and its dosing in US patients with atrial fibrillation: results from the outcomes registry for better informed treatment of atrial fibrillation.

Ansell, J; Chang, P; Ezekowitz, MD; Fonarow, GC; Gersh, Bernard John; Holmes, DaJuanicia; Hylek, EM; ... (15 authors) (J Am Heart Assoc, 2013-11-25)

BACKGROUND: Dabigatran is a novel oral anticoagulant approved for thromboprophylaxis in atrial fibrillation. Adoption patterns of this new agent in community practice are unknown. METHODS AND RESULTS: We studied patterns ...

Compliance with results reporting at ClinicalTrials.gov.

Anderson, ML; Califf, Robert M; Chiswell, K; Peterson, Eric David; Tasneem, Asba; Topping, J (N Engl J Med, 2015-03-12)

BACKGROUND: The Food and Drug Administration Amendments Act (FDAAA) mandates timely reporting of results of applicable clinical trials to ClinicalTrials.gov. We characterized the proportion of applicable clinical trials ...

Effectiveness and Safety of Aldosterone Antagonist Therapy Use Among Older Patients With Reduced Ejection Fraction After Acute Myocardial Infarction.

Das, S; de Lemos, JA; Fonarow, GC; Peng, SA; Peterson, Eric David; Vora, Amit Navin; Wang, TY (J Am Heart Assoc, 2016-01-21)

BACKGROUND: While aldosterone antagonists have proven benefit among post-myocardial infarction (MI) patients with low ejection fraction (EF), how this treatment is used among older MI patients in routine practice is not ...

Short- and long-term rehospitalization and mortality for heart failure in 4 racial/ethnic populations.

Bhatt, DL; Eapen, Zubin John; Fonarow, GC; Heidenreich, Paul A; Hernandez, Adrian Felipe; Krim, SR; Liang, Li; ... (11 authors) (J Am Heart Assoc, 2014-10-16)

BACKGROUND: The degree to which outcomes following hospitalization for acute heart failure (HF) vary by racial and ethnic groups is poorly characterized. We sought to compare 30-day and 1-year rehospitalization and mortality ...