Skip to main content
Duke University Libraries
DukeSpace Scholarship by Duke Authors
  • Login
  • Ask
  • Menu
  • Login
  • Ask a Librarian
  • Search & Find
  • Using the Library
  • Research Support
  • Course Support
  • Libraries
  • About
Search 
  •   DukeSpace
  • Duke Scholarly Works
  • Scholarly Articles
  • Search
  •   DukeSpace
  • Duke Scholarly Works
  • Scholarly Articles
  • Search
JavaScript is disabled for your browser. Some features of this site may not work without it.

Search

Show Advanced FiltersHide Advanced Filters

Filters

Use filters to refine the search results.

Now showing items 1-6 of 6

  • Sort Options:
  • Relevance
  • Title Asc
  • Title Desc
  • Issue Date Asc
  • Issue Date Desc
  • Results Per Page:
  • 5
  • 10
  • 20
  • 40
  • 60
  • 80
  • 100
Thumbnail

Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor. 

Cotecchia, S; Schwinn, DA; Randall, RR; Lefkowitz, RJ; Caron, MG; Kobilka, BK (Proc Natl Acad Sci U S A, 1988-10)
The cDNA for the Syrian hamster alpha 1-adrenergic receptor has been cloned with oligonucleotides corresponding to the partial amino acid sequence of the receptor protein purified from DDT1MF-2 smooth muscle cells. The deduced ...
Thumbnail

cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure. 

Collins, S; Bouvier, M; Bolanowski, MA; Caron, MG; Lefkowitz, RJ (Proc Natl Acad Sci U S A, 1989-07)
In addition to conveying cellular responses to an effector molecule, receptors are often themselves regulated by their effectors. We have demonstrated that epinephrine modulates both the rate of transcription of the beta ...
Thumbnail

Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism. 

Leeb-Lundberg, LM; Cotecchia, S; Lomasney, JW; DeBernardis, JF; Lefkowitz, RJ; Caron, MG (Proc Natl Acad Sci U S A, 1985-09)
DDT1 MF-2 cells, which are derived from hamster vas deferens smooth muscle, contain alpha 1-adrenergic receptors (54,800 +/- 2700 sites per cell) that are coupled to stimulation of inositol phospholipid metabolism. Incubation ...
Thumbnail

cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor. 

Kobilka, BK; Dixon, RA; Frielle, T; Dohlman, HG; Bolanowski, MA; Sigal, IS; Yang-Feng, TL; ... (10 authors) (Proc Natl Acad Sci U S A, 1987-01)
We have isolated and sequenced a cDNA encoding the human beta 2-adrenergic receptor. The deduced amino acid sequence (413 residues) is that of a protein containing seven clusters of hydrophobic amino acids suggestive of ...
Thumbnail

Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor. 

Benovic, JL; Strasser, RH; Caron, MG; Lefkowitz, RJ (Proc Natl Acad Sci U S A, 1986-05)
Agonist-promoted desensitization of adenylate cyclase is intimately associated with phosphorylation of the beta-adrenergic receptor in mammalian, avian, and amphibian cells. However, the nature of the protein kinase(s) involved ...
Thumbnail

Inhibition of beta-adrenergic receptor kinase prevents rapid homologous desensitization of beta 2-adrenergic receptors. 

Lohse, MJ; Lefkowitz, RJ; Caron, MG; Benovic, JL (Proc Natl Acad Sci U S A, 1989-05)
Homologous (agonist-specific) desensitization of beta-adrenergic receptors (beta ARs) is accompanied by and appears to require phosphorylation of the receptors. We have recently described a novel protein kinase, beta AR ...

Make Your Work Available Here

How to Deposit

Browse

All of DukeSpaceCommunities & CollectionsAuthorsTitlesTypesBy Issue DateDepartmentsAffiliations of Duke Author(s)SubjectsBy Submit DateThis CollectionAuthorsTitlesTypesBy Issue DateDepartmentsAffiliations of Duke Author(s)SubjectsBy Submit Date

My Account

LoginRegister

Discover

AuthorCaron, MG (6)Lefkowitz, RJ (6)Benovic, JL (2)Bolanowski, MA (2)Cotecchia, S (2)Kobilka, BK (2)Bouvier, M (1)Collins, S (1)DeBernardis, JF (1)Dixon, RA (1)... View MoreDate Issued1989 (2)1985 (1)1986 (1)1987 (1)1988 (1)TypeJournal article (6)SubjectAnimals (6)
Cricetinae (6)
Receptors, Adrenergic, beta (4)Base Sequence (3)Phosphorylation (3)Cell Line (2)Cell Membrane (2)DNA (2)Humans (2)Kinetics (2)... View MoreAffiliation of Duke Author(s)
Basic Science Departments (6)
Biochemistry (6)Cell Biology (6)Chemistry (6)Clinical Science Departments (6)Duke (6)Duke Cancer Institute (6)Duke Institute for Brain Sciences (6)Institutes and Centers (6)
Institutes and Provost's Academic Units (6)
... View More
Duke University Libraries

Contact Us

411 Chapel Drive
Durham, NC 27708
(919) 660-5870
Perkins Library Service Desk

Digital Repositories at Duke

  • Report a problem with the repositories
  • About digital repositories at Duke
  • Accessibility Policy
  • Deaccession and DMCA Takedown Policy

TwitterFacebookYouTubeFlickrInstagramBlogs

Sign Up for Our Newsletter
  • Re-use & Attribution / Privacy
  • Support the Libraries
Duke University