Now showing items 1-5 of 5
stpm: an R package for stochastic process model.
(BMC Bioinformatics, 2017-02-23)
BACKGROUND: The Stochastic Process Model (SPM) represents a general framework for modeling the joint evolution of repeatedly measured variables and time-to-event outcomes observed in longitudinal studies, i.e., SPM relates ...
Cardiovascular comorbidities and survival of lung cancer patients: Medicare data based analysis.
(Lung Cancer, 2017-06-05)
OBJECTIVES: To evaluate the role of cardiovascular disease (CVD) comorbidity in survival of patients with non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: The impact of seven CVDs (at the time of NSCLC diagnosis ...
Uncoupling associations of risk alleles with endophenotypes and phenotypes: insights from the ApoB locus and heart-related traits.
(Aging Cell, 2017-02)
Traditionally, genomewide association studies (GWAS) have emphasized the benefits of large samples in the analyses of age-related traits rather than their specific properties. We adopted a realistic concept of genetic ...
Theory of partitioning of disease prevalence and mortality in observational data.
(Theor Popul Biol, 2017-04)
In this study, we present a new theory of partitioning of disease prevalence and incidence-based mortality and demonstrate how this theory practically works for analyses of Medicare data. In the theory, the prevalence of ...
The Survival of Spouses Marrying Into Longevity-Enriched Families.
(J Gerontol A Biol Sci Med Sci, 2017-01)
BACKGROUND: Studies of longevity-enriched families are an important tool to gain insight into the mechanisms of exceptionally long and healthy lives. In the Long Life Family Study, the spouses of the members of ...