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A novel inflammatory biomarker, GlycA, associates with disease activity in rheumatoid arthritis and cardio-metabolic risk in BMI-matched controls.

AbouAssi, H; Bartlett, David Bruce; Bateman, LA; Connelly, MA; Huebner, JL; Huffman, Kim Marie; Kraus, Virginia Byers; ... (11 authors) (Arthritis Res Ther, 2016-04-12)

BACKGROUND: RA and CVD both have inflammation as part of the underlying biology. Our objective was to explore the relationships of GlycA, a measure of glycosylated acute phase proteins, with inflammation and cardiometabolic ...

Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial.

Bain, James R; Huffman, Kim Marie; Kraus, Virginia Byers; Kraus, William Erle; Landerman, LR; Muehlbauer, Michael J; Newgard, Christopher Bang; ... (12 authors) (PLoS One, 2012)

OBJECTIVES: To determine if caloric restriction (CR) would cause changes in plasma metabolic intermediates in response to a mixed meal, suggestive of changes in the capacity to adapt fuel oxidation to fuel availability or ...

Critical appraisal of four IL-6 immunoassays.

Huffman, Kim Marie; Kraus, Virginia Byers; Kraus, William Erle; Thompson, DK (PLoS One, 2012)

BACKGROUND: Interleukin-6 (IL-6) contributes to numerous inflammatory, metabolic, and physiologic pathways of disease. We evaluated four IL-6 immunoassays in order to identify a reliable assay for studies of metabolic and ...

Exercise-induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity.

Bain, James R; Bateman, LA; Huffman, Kim Marie; Kraus, Virginia Byers; Kraus, William Erle; Muehlbauer, Michael J; Newgard, Christopher Bang; ... (11 authors) (Diabetes Care, 2011-01)

OBJECTIVE: To understand relationships between exercise training-mediated improvements in insulin sensitivity (S(I)) and changes in circulating concentrations of metabolic intermediates, hormones, and inflammatory mediators. ...