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Gene expression signatures of radiation response are specific, durable and accurate in mice and humans. 

Chao, Nelson J; Chute, JP; Dressman, HK; Ginsburg, Geoffrey Steven; Himburg, Heather; Meadows, Sarah K; Muramoto, Garrett G; ... (10 authors) (PLoS One, 2008-04-02)
BACKGROUND: Previous work has demonstrated the potential for peripheral blood (PB) gene expression profiling for the detection of disease or environmental exposures. METHODS AND FINDINGS: We have sought to determine the ...
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Co-activation of the amygdala, hippocampus and inferior frontal gyrus during autobiographical memory retrieval. 

Greenberg, Daniel L; Rice, Heather J; Cooper, Julie J; Cabeza, Roberto; Rubin, David C; Labar, Kevin S (Neuropsychologia, 2005)
Functional MRI was used to investigate the role of medial temporal lobe and inferior frontal lobe regions in autobiographical recall. Prior to scanning, participants generated cue words for 50 autobiographical memories and ...
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Emotional intensity predicts autobiographical memory experience. 

Talarico, Jennifer M; LaBar, Kevin S; Rubin, David C (Mem Cognit, 2004-10)
College students generated autobiographical memories from distinct emotional categories that varied in valence (positive vs. negative) and intensity (high vs. low). They then rated various perceptual, cognitive, and emotional ...
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Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice. 

Bohn, Laura M; Gainetdinov, Raul R; Sotnikova, Tatyana D; Medvedev, Ivan O; Lefkowitz, Robert J; Dykstra, Linda A; Caron, Marc G (J Neurosci, 2003-11-12)
The reinforcing and psychomotor effects of morphine involve opiate stimulation of the dopaminergic system via activation of mu-opioid receptors (muOR). Both mu-opioid and dopamine receptors are members of the G-protein-coupled ...
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Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice. 

Bohn, Laura M; Lefkowitz, Robert J; Caron, Marc G (J Neurosci, 2002-12-01)
Morphine induces antinociception by activating mu opioid receptors (muORs) in spinal and supraspinal regions of the CNS. (Beta)arrestin-2 (beta)arr2), a G-protein-coupled receptor-regulating protein, regulates the muOR in ...
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Association of MDMA/ecstasy and other substance use with self-reported sexually transmitted diseases among college-aged adults: a national study. 

Wu, L-T; Ringwalt, CL; Patkar, AA; Hubbard, RL; Blazer, DG (Public health, 2009-08-04)
MDMA/ecstasy use among college students has increased and reportedly leads to risky sexual behaviours. However, little is known about its association with sexually transmitted diseases (STDs). To evaluate this public health ...
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Using functional magnetic resonance imaging in psychotherapy research: a brief introduction to concepts, methods, and task selection. 

Carrig, Madeline M; Kolden, Gregory G; Strauman, Timothy J (Psychother Res, 2009-07)
Functional magnetic resonance imaging (fMRI) has become an increasingly important methodology in the study of psychotherapy outcome and process. In this article, the authors offer a brief introduction to the use of fMRI ...
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The variety of ecstasy/MDMA users: results from the National Epidemiologic Survey on alcohol and related conditions. 

Wu, Li-Tzy; Parrott, Andy C; Ringwalt, Christopher L; Yang, Chongming; Blazer, Dan G (The American journal on addictions, 2009-11)
This study investigates the potential heterogeneity of ecstasy or MDMA (3,4-methylenedioxy-N-methylamphetamine) users. Data came from the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). ...
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The high prevalence of substance use disorders among recent MDMA users compared with other drug users: Implications for intervention. 

Wu, Li-Tzy; Parrott, Andy C; Ringwalt, Christopher L; Patkar, Ashwin A; Mannelli, Paolo; Blazer, Dan G (Addictive behaviors, 2009-08)
In light of the resurgence in MDMA use and its association with polysubstance use, we investigated the 12-month prevalence of substance use disorders (SUDs) among adult MDMA users to determine whether they are at risk of ...
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An item response theory modeling of alcohol and marijuana dependences: a National Drug Abuse Treatment Clinical Trials Network study. 

Wu, Li-Tzy; Pan, Jeng-Jong; Blazer, Dan G; Tai, Betty; Stitzer, Maxine L; Brooner, Robert K; Woody, George E; ... (9 authors) (Journal of studies on alcohol and drugs, 2009-05)
OBJECTIVE:The aim of this study was to examine psychometric properties of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), diagnostics criteria for alcohol and marijuana dependences among ...
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AuthorWu, Li-Tzy (38)Blazer, Dan G (11)Schlenger, William E (11)Patkar, Ashwin A (10)Pilowsky, Daniel J (8)Ringwalt, Christopher L (8)Rubin, David C (7)LaBar, Kevin S (5)Lefkowitz, Robert J (5)Mannelli, Paolo (5)... View MoreDate Issued2009 (24)2008 (16)2004 (12)2007 (8)2003 (7)2005 (6)2006 (6)2002 (4)2000 (3)2001 (2)Type
Journal article (88)
SubjectHumans (73)Female (55)Male (55)Adult (39)Adolescent (37)United States (34)Substance-Related Disorders (28)Child (20)Prevalence (18)Middle Aged (17)... View MoreAffiliation of Duke Author(s)
Clinical Science Departments (88)
Duke (88)
Institutes and Provost's Academic Units (88)
School of Medicine (88)
University Institutes and Centers (88)
Institutes and Centers (78)Duke Institute for Brain Sciences (74)Medicine (65)Psychiatry & Behavioral Sciences (65)Sanford School of Public Policy (56)... View More
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