Displacement of particles in microfluidics by laser-generated tandem bubbles.
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The dynamic interaction between laser-generated tandem bubble and individual polystyrene particles of 2 and 10 μm in diameter is studied in a microfluidic channel (25 μm height) by high-speed imaging and particle image velocimetry. The asymmetric collapse of the tandem bubble produces a pair of microjets and associated long-lasting vortices that can propel a single particle to a maximum velocity of 1.4 m∕s in 30 μs after the bubble collapse with a resultant directional displacement up to 60 μm in 150 μs. This method may be useful for high-throughput cell sorting in microfluidic devices.
Published Version (Please cite this version)10.1063/1.3511538
Publication InfoLautz, Jaclyn; Sankin, Georgy; Yuan, Fang; & Zhong, Pei (2010). Displacement of particles in microfluidics by laser-generated tandem bubbles. Appl Phys Lett, 97(18). pp. 183701. 10.1063/1.3511538. Retrieved from https://hdl.handle.net/10161/3246.
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Professor in the Department of Mechanical Engineering and Materials Science
My research focuses on four broad and interconnected areas in the emerging field of therapeutic ultrasound, which is located at the interface of engineering, biology and clinical medicine. Current research interests in my group include: Ultrasound-targeted gene delivery and activation Synergistic combination of high-intensity focused ultrasound (HIFU) and immunotherapy for cancer treatment Innovations in shock wave lithotripsy (SWL) technology</l