Browsing Duke Dissertations by Submit Date
Now showing items 21-40 of 4029
-
Advancements in Probabilistic Machine Learning and Causal Inference for Personalized Medicine
(2019)In this dissertation, we present four novel contributions to the field of statistics with the shared goal of personalizing medicine to individual patients. These methods are developed to directly address problems in health ... -
Three Essays on Energy and Development Economics
(2019)Global energy-use patterns are characterized by deep inequality. Electricity is indispensable for households, clinics, schools and firms, yet over a billion people live without it. At the same time, nearly three billion ... -
Architecture and the Performance of Citizenship in a Global City: Singapore, 1965-2015
(2019)In this dissertation, I present the ways in which architecture was used to perform citizenship in post-colonial Singapore from 1965-2015. During the first fifty years of independence, architects, alongside other artists ... -
Networks of Competition: The Foundation of Market Structure and Competitive Constraint in Organizational Ecosystems
(2019)Research in organizational ecology demonstrates that an organization’s competitive position within its market is highly associated with its survival chances, and that patterns of competitive constraint among organizations ... -
Essays on the Determinants of Public Funding for Universities and the Impact on Innovation and Entrepreneurship
(2019)This dissertation is comprised of three studies that investigate the implications and determinants of public funding for universities. The first chapter lays down the foundation for the other two studies. I discuss ... -
Regulation of Synaptic Processing in the Cerebellar Cortex by Neuromodulation and Protein Trafficking
(2019)Examining the coordination of excitatory and inhibitory (E/I) activity within cortical circuits is a fundamental approach to understanding normal and aberrant circuit function. Alteration to this E/I coordination is one ... -
The Poetics of Labor: Visions of Work and Community in England, 1730-1890
(2019)The Poetics of Labor argues for a reconsideration of how manual labor functions within poetic texts in eighteenth- and nineteenth-century England. As scholarship over the last forty years and onward has demonstrated, ... -
Big House: Women, Prison, and the Domestic
(2019)Big House: Women, Prison, and the Domestic, addresses the development of the contemporary US carceral state, foregrounding the confinement and control of women and the evolving ideological frameworks and disciplinary techniques ... -
Management and Optimal Use of Soil and Water Resources in Ecohydrological Systems
(2019)Human activities are shifting hydrological and biogeochemical cycles further from their natural states, often resulting in negative impacts on the environment. Because of increased pressures due to climate change and population ... -
Bayesian Dynamic Modeling and Forecasting of Count Time Series
(2019)Problems of forecasting related time series of counts arise in a diverse array of applications such as consumer sales, epidemiology, ecology, law enforcement, and tourism. Characteristics of high-frequency count data including ... -
I. Design, Synthesis, and Biological Characterization of Subglutinol A Analogs II. Synthetic Efforts Towards the Total Synthesis of RhodojaponinB
(2019)Natural products have a significant influence on the development of chemical treatments for diseases as well as the exploration of biological pathways and are still a major pipeline for novel drug discovery. However, their ... -
Novel Algorithms and Tools for Computational Protein Design with Applications to Drug Resistance Prediction, Antibody Design, Peptide Inhibitor Design, and Protein Stability Prediction
(2019)Proteins are biological macromolecules made up of amino acids. Proteins range from enzymes to antibodies and perform their functions through a variety of mechanisms, including through protein-protein interactions (PPIs). ... -
Diagrammatics in Categorification and Compositionality
(2019)In the present work, I explore the theme of diagrammatics and their capacity to shed insight on two trends—categorification and compositionality—in and around contemporary category theory. The work begins with an introduction ... -
The Real Effects of Algorithmic Trading
(2019)Prior literature finds that algorithmic trading (AT) benefits the financial market by improving liquidity and accelerating the incorporation of existing information into prices. This paper shows that AT also has negative ... -
Transverse Homology and Transverse Nonsimplicity
(2019)We show that if a transversely nonsimple knot has two braid representatives, related by a negative flype, that can be distinguished by augmentation numbers of transverse homology, then an infinite family of transversely ... -
Brewing Development: Multinational Alcohol Companies, the Neo-Concessionary State, and the Politics of Industrialization in Ethiopia
(2019)This dissertation examines the politics of industry and industrialization in Ethiopia. I analyze how multinational alcohol companies and the Ethiopian state are brewing development, meaning spurring the creation of industrial ... -
Culture, Capture, and Disease: Shrimp Production in the Age of Industrial Aquaculture
(2019)This dissertation focuses on the relationship of industrial shrimp aquaculture and shrimp diseases, with an emphasis on the agency of disease in shaping the history of shrimp production. Shrimp aquaculture is concentrated ... -
Improved Visualization and Quantification for Hyperpolarized 129Xe MRI
(2019)In Pulmonary diseases, such as chronic obstructed pulmonary diseases (COPD), fibrosis, and asthma, are responsible for substantial health and financial burden in the world. In 2016, COPD claimed more than 3 million lives, ... -
OMISSIONS, CAUSATION, AND MODALITY
(2019)In The Neverending Story (1984), “the nothing” was spreading throughout Fantasia. This is terrifying not just because of the nature of the west-German fantasy film but also because nothing—non-being—was represented as something ... -
Microalgae Growth in Recycled Cultivation Water
(2019)A cost-saving strategy of large-scale algae cultivation that can lead to more economical production of algal food, feed, and fuels involves reusing the cultivation water after algae harvesting. Few studies have focused on ...
