Now showing items 1-2 of 2

    • Distinct functions of POT1 at telomeres. 

      Barrientos, KS; Kendellen, MF; Freibaum, BD; Armbruster, BN; Etheridge, KT; Counter, CM (Mol Cell Biol, 2008-09)
      The mammalian protein POT1 binds to telomeric single-stranded DNA (ssDNA), protecting chromosome ends from being detected as sites of DNA damage. POT1 is composed of an N-terminal ssDNA-binding domain and a C-terminal protein ...
    • Knowledge-based IMRT treatment planning for prostate cancer. 

      Chanyavanich, V; Das, SK; Lee, WR; Lo, JY (Med Phys, 2011-05)
      PURPOSE: To demonstrate the feasibility of using a knowledge base of prior treatment plans to generate new prostate intensity modulated radiation therapy (IMRT) plans. Each new case would be matched against others in the ...