Browsing Duke Dissertations by Submit Date
Now showing items 1-20 of 4537
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Homologous Recombination Outcomes of Double-Strand Break- initiated Events in Saccharomyces cerevisiae
(2020)Homologous recombination (HR) is responsible for repairing otherwise lethal DNA double-strand breaks (DSBs) using a homologous donor template. The work in this dissertation, using the budding yeast Saccharomyces cerevisiae ... -
In Search of "Friendship": Energy Policy, Trade, and Varieties of Socialism in the Soviet Bloc, 1872-1984
(2020)“In Search of Friendship” attempts to set straight the confounding record on Russian oil in the twentieth century. Engaging a rich literature centered on questions of national energy dependency, a broad term denoting fraught ... -
Volumetric Acoustic Radiation Force Impulse Imaging Using Intracardiac Echocardiography
(2020)Intracardiac echocardiography (ICE) based elastography methods have the potential to be useful for a number of clinical purposes including monitoring of ablation lesion formation and myocardial substrate characterization. ... -
Security and Robustness in Neuromorphic Computing and Deep Learning
(2020)Machine learning (ML) has been promoting fast in the recent decade. Among many ML algorithms, inspired by biological neural systems, neural networks (NNs) and neuromorphic computing systems (NCSs) achieve state-of-the-art ... -
Essays on the Complexities of Social Inequalities and Health Disparities
(2020)In this dissertation, I conduct three studies focusing on differences in social groups and their health outcomes or opinions related to medical practices. In Chapter 1, I outline each study and its findings.Chapter 2 focuses ... -
The Use and Abuse of Technology: Reconsidering the Ethics of Civil Disobedience, Leaking, and Intellectual Property for the Information Age
(2020)The suspicion that the advent of the internet marks some sort of qualitative change in the development of the human affairs motivates much diagnosis but less instruction about the contemporary political moment. Are there ... -
Essays on the Political Economy of Authoritarian Rule
(2020)This dissertation consists of three essays pertaining to the political economy of authoritarian rule. The first essay contributes a missing piece to the puzzle of the "Great Divergence" between Western Europe and East Asia ... -
Algorithms for Two-sided Online Marketplaces
(2020)The recent emergence of new successful two-sided online platforms has transformed the concept of a marketplace. Numerous two-sided mechanism design problems, including those studied in this thesis, are motivated by these ... -
Elucidating Atmospheric Turbulence Across Scales in Numerical Models: Land-Atmosphere Interaction Controls of Moist Processes
(2020)This research aims to understand the development of the atmospheric energy spectrum and energy transfer mechanisms across scales. A clear understanding of energy spectrum development and transfer mechanisms is necessary ... -
Rethinking Judicial Independence in Democracy and Autocracy
(2020)Building independent courts is a commitment by political leaders that they are willing to tie their hands, restrain their (often arbitrary) power, and respect judicial decisions even if the courts rule against them. But ... -
Transcription Factor-Centric Approaches to Identify Regulatory Driver Mutations in Cancer
(2020)Most previous efforts to identify cancer driver mutations have focused on protein-coding genes. In recent years, the decreasing costs of DNA sequencing have enabled whole-genome sequencing (WGS) studies of thousands of tumor ... -
From Layered Intrusions to Mid-Ocean Ridges: The Petrography and Geochemistry of Basaltic Magmas
(2020)The geochemical evolution of basaltic magmas, in a variety of settings, has been the subject of countless studies. In some instances, basaltic magmas evolve to form economic transition and precious metal ore bodies. The ... -
Two Algorithmic Schemes for Geometric Bipartite Matching and Transportation
(2020)Given n red points and n blue points in d-dimensional space and a distance function, the geometric bipartite matching problem is to find a matching of red points to blue points, such that the sum of distances between the ... -
Parenting After Stroke
(2020)Stroke is the fifth leading cause of death in the United States and the leading cause of disability. Historically, stroke has been considered a condition limited to older adults. However, stroke is affecting an increasing ... -
Matrona Visa: Women's Public Visibility and Civic Identity in Hispania Tarraconensis
(2020)This dissertation examines evidence for the public visibility of elite women in Roman cities in the province of Hispania Tarraconenesis from the first through the third centuries C. E. By focusing on the epigraphic evidence ... -
Essays on Financial Econometrics
(2020)This dissertation contains my research results on two topics of nancial econometrics.The rst topic is jump regression where the observation selection procedure can beviewed as the analogy of dimension reduction for the classical ... -
Advances in Bayesian Hierarchical Modeling with Tree-based Methods
(2020)Developing flexible tools that apply to datasets with large size and complex structure while providing interpretable outputs is a major goal of modern statistical modeling. A family of models that are especially suitable ... -
Design and Characterization of Carbon Nanomaterial-Based Electrodes for Use in Harsh Environments
(2020)Electrode degradation in harsh environments is a problem that plagues many devices. Traditional metallic and carbon-based electrodes are often reactive and can fail over time, leading to reduced efficiency and increased ... -
Nonlinear Energy Harvesting With Tools From Machine Learning
(2020)Energy harvesting is a process where self-powered electronic devices scavenge ambient energy and convert it to electrical power. Traditional linear energy harvesters which operate based on linear resonance work well only ... -
Characterization of the O-GlcNAc Modification on the COPII Outer Coat
(2020)The coat protein complex II (COPII) traffics cargoes from the endoplasmic reticulum to the Golgi and is an essential step early in the secretory pathway. COPII consists of five proteins required for in vitro vesicle formation: ...
