Browsing Duke Dissertations by Submit Date
Now showing items 1-20 of 3452
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Essays on the economics of higher education: Investigating college major choice
(2017)This dissertation consists of two separate essays on major choice in higher education. In the first chapter, I investigate how differences in information affect students' major choices over time. Since college has such a ... -
Efficient Design of Electricity Market Clearing Mechanisms with Increasing Levels of Renewable Generation and Carbon Price
(2017)Increased use of wind energy in electricity systems can help reduce green house gas emissions and enhance energy security. However, the traditional scheduling and dispatching processes used to ensure the cost-effective and ... -
High Resolution Continuous Active Sonar
(2017)This dissertation presents waveform design and signal processing methods for continuous active sonar (CAS). The work presented focuses on methods for achieving high range, Doppler, and angular resolution, while maintaining ... -
Stormwater and organic matter in the urban stream continuum
(2017)Dissolved organic matter (DOM) is present in all natural waters and modulatesaquatic ecosystems by absorbing light and heat, and because it comprises a complexmixture of organic molecules including amino acids, sugars, ... -
A mitotic DNA damage response requiring FANCD2 enables mitosis with broken DNA
(2017)In order to maintain genome integrity cells employ a set of well conserved DNA damage checkpoints. DNA damage checkpoints are active during interphase and serve to prevent mitosis with broken DNA. Mitosis with broken DNA ... -
The Role of Light and Alkylamines in Controlling the Growth of Copper Nanowires
(2017)The synthesis of various anisotropically assembled metal structures has increased at a rapid pace in the past two decades in order produce nanomaterials with unique properties that can meet the demands of future electronics ... -
Probing and Managing Photo-Induced Electronically Excited-State Dynamics of Molecular to Nanoscale Systems
(2017)Light-matter interactions, spectroscopically depicted by the generation and decay of materials’ photo-excited states, are the core to majority of modern optic and optoelectronic technologies that include photovoltaics ... -
Integrative Analysis of the Genomics of the Human Glucocorticoid Response
(2017)Glucocorticoids (GCs) are potent steroid hormones that regulate immunity and metabolism, and do so primarily by activating the transcription factor glucocorticoid receptor (GR). Once activated, GR binds to thousands of ... -
The Ontogeny of Vaccine-Induced HIV-1 Glycan-Reactive Antibodies
(2017)The HIV-1 envelope (Env) glycoprotein trimer expressed on the virion surface is the target for both non-neutralizing and neutralizing antibodies (nAbs). In both infection and vaccination, the dominant neutralizing antibody ... -
Mechanism of C-C Bond Forming Radical SAM Enzymes in Antifungal Natural Product and Molybdenum Cofactor Biosynthesis
(2017)Naturally occurring small molecules are often characterized by their unique and complex structures critical for their biological functions. Many of these natural product biosynthetic pathways involve radical S-adenosylmethionine ... -
Development and Application of Mass Spectrometry-Based Approaches for Thermodynamic Analysis of Protein-Ligand Binding Interactions
(2017)The characterization of protein stability changes and protein-ligand interactions on the proteomic scale is important for understanding the biology of cellular processes. The identification and quantification of protein-ligand ... -
Quantitative description of residual helical structure for λ-repressor N-terminal domain in the unfolded state
(2017)Proteins can form residual compactness in the unfolded state. Among different types of residual compactness, residual helical structure is an important type of local compactness that can propagate through the formation of ... -
A New Hybrid Free-Wake Model for Wind Turbine Aerodynamics with Application to Wake Steering
(2017)Wind energy has emerged as one of the most promising and rapidly growing renewable energy technologies in the United States and over the world. The offshore wind energy is of special interest because it has more consistent ... -
Toward a Prehistory of the Fantastic: The Imagination of Alterity in the Long Eighteenth Century
(2017)Dreams of Reason: The Imagination of Alterity in the Long Eighteenth Century historicizes the assumptions underlying theories of fantastic or non-realist genre fiction. In the course of a comparative analysis of the lunar ... -
Spatial and Temporal Drivers of Coastal Wetland Formation and Persistence
(2017)Coastal wetlands are complex biogeomorphic systems that provide important ecosystem services, but our current understanding of salt marsh evolution and persistence is based on models and empirical studies of limited spatial ... -
Mechanisms of Specificity in Neuronal Activity-regulated Gene Transcription
(2017)The ability to convert sensory stimuli into long-lasting changes in brain function is essential for animals to interact with and learn from their environment. This process is achieved by encoding sensory stimuli into ... -
Conservation in the Human Landscape
(2017)The protection of global biodiversity and the conservation of the earth’s natural resources are paramount to future wellbeing of mankind. Humans are a hugely influential part of the global ecosystem, and the ways in which ... -
Child's Play: Psychoanalysis and the Politics of the Clinic
(2017)In 1925, Sigmund Freud wrote a short preface for August Aichhorn’s forthcoming book, Wayward Youth. There, Freud hailed ‘the child’ as the future of psychoanalysis, declaring that “[o]f all the fields in which psychoanalysis ... -
Kinetics and Energetics of Feeding Behaviors in Daubentonia madagascariensis
(2017)The primary aim of this thesis was to quantify the ways Daubentonia uses its specialized feeding apparatus during naturalistic feeding behaviors. This can be divided into two main objectives. The first objective was to ... -
Structural and Biochemical Investigation of the Molecular Mechanisms of Human Exonuclease I and Characterization of Its Protein-Protein Interactions
(2017)Human exonuclease 1 (hExo1) is a RAD2/XPG family 5’ structure-specific nuclease and is important for various central DNA metabolic processes including replication, recombination, and repair. Its defects disrupt genome ...
