Now showing items 1-4 of 4

    • Glucose metabolism and p53 in leukemia 

      Mason, Emily Ferguson (2011)
      Healthy cells require input from growth factor signaling pathways to maintain cell metabolism and survival. Growth factor deprivation induces a loss of glucose metabolism that contributes to cell death in this context, ...
    • Mechanisms by which p53 Regulates Radiation-induced Carcinogenesis and Myocardial Injury 

      Lee, Chang-Lung (2012)
      Radiation therapy can cause acute toxicity and long-term side effects in normal tissues. Because part of the acute toxicity of radiation is due to p53-mediated apoptosis, blocking p53 during irradiation can protect some ...
    • Molecular Mechanisms of Airway Epithelial Progenitor Cell Maintenance and Repair. 

      Farin, Alicia M. (2016)
      The lungs are vital organs whose airways are lined with a continuous layer of epithelial cells. Epithelial cells in the distal most part of the lung, the alveolar space, are specialized to facilitate gas exchange. Proximal ...
    • The role of TRIM39 in cell cycle and apoptosis 

      Huang, Nai-Jia (2013)
      Within individual cells, the opposing processes of proliferation and apoptosis are precisely regulated. When this regulatory balance is interrupted, cells may become abnormal or even transformed. Understanding how to reverse ...