Now showing items 1-10 of 12
Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation.
(J Clin Invest, 2011-03)
Allergic asthma is characterized by airway hyperresponsiveness, inflammation, and a cellular infiltrate dominated by eosinophils. Numerous epidemiological studies have related the exacerbation of allergic asthma with an ...
Optimized approach to decision fusion of heterogeneous data for breast cancer diagnosis.
(Med Phys, 2006-08)
As more diagnostic testing options become available to physicians, it becomes more difficult to combine various types of medical information together in order to optimize the overall diagnosis. To improve diagnostic performance, ...
Three-dimensional computer generated breast phantom based on empirical data
(MEDICAL IMAGING 2008: PHYSICS OF MEDICAL IMAGING, PTS 1-3, 2008)
Distinct functions of POT1 at telomeres.
(Mol Cell Biol, 2008-09)
The mammalian protein POT1 binds to telomeric single-stranded DNA (ssDNA), protecting chromosome ends from being detected as sites of DNA damage. POT1 is composed of an N-terminal ssDNA-binding domain and a C-terminal protein ...
Harmonic source wavefront aberration correction for ultrasound imaging.
(J Acoust Soc Am, 2011-01)
A method is proposed which uses a lower-frequency transmit to create a known harmonic acoustical source in tissue suitable for wavefront correction without a priori assumptions of the target or requiring a transponder. The ...
Functional neuroimaging of autobiographical memory.
(Trends Cogn Sci, 2007-05)
Functional neuroimaging studies of autobiographical memory have grown dramatically in recent years. These studies are important because they can investigate the neural correlates of processes that are difficult to study ...
Epigenetic regulation of the nitrosative stress response and intracellular macrophage survival by extraintestinal pathogenic Escherichia coli.
(Mol Microbiol, 2012-03)
Extraintestinal pathogenic Escherichia coli (ExPEC) reside in the enteric tract as a commensal reservoir, but can transition to a pathogenic state by invading normally sterile niches, establishing infection and disseminating ...
An entirely cell-based system to generate single-chain antibodies against cell surface receptors.
(J Mol Biol, 2008-05-30)
The generation of recombinant antibodies (Abs) using phage display is a proven method to obtain a large variety of Abs that bind with high affinity to a given antigen. Traditionally, the generation of single-chain Abs depends ...
A PK2/Bv8/PROK2 antagonist suppresses tumorigenic processes by inhibiting angiogenesis in glioma and blocking myeloid cell infiltration in pancreatic cancer.
(PLoS One, 2013)
Infiltration of myeloid cells in the tumor microenvironment is often associated with enhanced angiogenesis and tumor progression, resulting in poor prognosis in many types of cancer. The polypeptide chemokine PK2 (Bv8, PROK2) ...
Knowledge-based IMRT treatment planning for prostate cancer.
(Med Phys, 2011-05)
PURPOSE: To demonstrate the feasibility of using a knowledge base of prior treatment plans to generate new prostate intensity modulated radiation therapy (IMRT) plans. Each new case would be matched against others in the ...