Now showing items 1-5 of 5
Intra-articular Clearance of Silk Microparticles and Macromolecules in Healthy and Arthritic Rat Knee Joints
Osteoarthritis (OA) is a degenerative disease of articular joints characterized by progressive deterioration of the cartilage lining, subchondral bone destruction and thickening of the joint capsule. These tissue changes ...
Self-organized Pattern Formation using Engineered Bacteria
Diverse mechanisms have been proposed to explain natural pattern formation processes, such as slime mold aggregation, feather branching, and tissue stratification. Regardless of the specific molecular interactions, the vast ...
Use of Human Blood-Derived Endothelial Progenitor Cells to Improve the Performance of Vascular Grafts
Synthetic small diameter vascular grafts fail clinically due to thrombosis and intimal hyperplasia. The attachment of endothelial cells (ECs) onto the inner lumen of synthetic small diameter vascular grafts can improve graft ...
Bacterial Communication and Cooperation: From Understanding to Applications
Bacteria communicate, coordinate, and cooperate as a population and this `social' behavior is key to their proliferation. Quorum sensing (QS) is the cell-cell communication mechanism by which bacteria sense their population ...
Genome Engineering Tools to Dissect Gene Regulation
Over the past several years genome and epigenome engineering has been propelled forward by CRISPR-Cas technologies. These prokaryotic defense systems work well in mammalian cells in a manner that is remarkably robust: they ...