Now showing items 1-3 of 3
Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation.
(J Clin Invest, 2011-03)
Allergic asthma is characterized by airway hyperresponsiveness, inflammation, and a cellular infiltrate dominated by eosinophils. Numerous epidemiological studies have related the exacerbation of allergic asthma with an ...
Mechanisms of specificity in neuronal activity-regulated gene transcription.
(Prog Neurobiol, 2011-08)
The brain is a highly adaptable organ that is capable of converting sensory information into changes in neuronal function. This plasticity allows behavior to be accommodated to the environment, providing an important evolutionary ...
B-lymphocyte effector functions in health and disease.
(Immunol Res, 2011-04)
B-lymphocytes have traditionally been thought to contribute to immunity and autoimmune disease through terminal differentiation into plasma cells that secrete antibody. However, studies in mice and recent clinical studies ...