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    Pharmacological targeting of the mitochondrial phosphatase PTPMT1. 

    Doughty-Shenton, D; Joseph, JD; Zhang, J; Pagliarini, DJ; Kim, Y; Lu, D; Dixon, JE; ... (8 authors) (J Pharmacol Exp Ther, 2010-05)
    The dual-specificity protein tyrosine phosphatases (PTPs) play integral roles in the regulation of cell signaling. There is a need for new tools to study these phosphatases, and the identification of inhibitors potentially ...
     

     

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    AuthorCasey, PJ (1)Dixon, JE (1)
    Doughty-Shenton, D (1)
    Joseph, JD (1)Kim, Y (1)Lu, D (1)Pagliarini, DJ (1)Zhang, J (1)Date Issued2010 (1)TypeJournal article (1)SubjectAnimals (1)
    Biguanides (1)
    Dose-Response Relationship, Drug (1)Dual Specificity Phosphatase 1 (1)Immunoblotting (1)Insulin (1)Islets of Langerhans (1)Mitochondria (1)Mitochondrial Proteins (1)Phosphorylation (1)... View MoreDepartmentBiochemistry (1)Affiliation of Duke Author(s)Basic Science Departments (1)Biochemistry (1)Duke (1)
    Duke Cancer Institute (1)
    Institutes and Centers (1)
    Pharmacology & Cancer Biology (1)
    School of Medicine (1)