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Spatiotemporal Dynamics of CaMKI During Structural Plasticity of Single Dendritic Spines
Multifunctional calcium/calmodulin dependent protein kinases (CaMKs) are key regulators of spine structural plasticity and long-term potentiation (LTP) in neurons. CaMKs have promiscuous and overlapping substrate recognition ...
Extracellular Signal-Regulated Kinase as an Integrative Synapse-to-Nucleus Signal
The late phase of long-term synaptic potentiation (LTP) at glutamatergic synapses, which is thought to underlie the long lasting memory (at least hours), requires gene transcription in the nucleus. However, it remains elusive ...