Mouse lemurs (genus Microcebus; Order Primates) are endemic to the island nation of Madagascar. These small, nocturnal primates offer a unique mammalian system ideally suited to study the patterns and processes of speciation, ...

How species adapt to their local environments over the course of evolution remains an important question that underlies much of modern biology. Though much has been learned, many questions remain unanswered on the interplay ...

Seasonal heterothermy—an orchestrated set of extreme physiological responses—is directly responsible for the over-winter survival of many mammalian groups living in seasonal environments. Historically, it was thought that ...

The maintenance of genetic variation for quantitative traits has long puzzled evolutionary biologists. Previous studies have effectively interrogated large genomic regions both in the greenhouse and field to understand the ...

While local adaptation has been frequently demonstrated via reciprocal transplant experiments, our understanding of the genetic basis of it remains minimal. There is a notable lack of studies that identify naturally segregating ...

In an attempt to gain more insight on functional evolution of cAMP-PKA pathway I have taken a comparative approach and examined functional interactions of cAMP-PKA signaling in well-studied yeast developmental programs and ...

Recombination occurs during meiosis to produce new allelic combinations in natural populations, and thus strongly affects evolutionary processes. The model system Drosophila has been crucial for understanding the mechanics ...

Although it has been known for many years that B-cyclin/CDK complexes regulate the assembly of the mitotic spindle and entry into mitosis, the full complement of relevant CDK targets has not been identified. It has previously ...

In an ever-changing world, evolution is an essential process that may allow organisms to adapt to their environment through natural selection. All evolutionary processes act through a single fundamental medium: genetic variation. ...

What evolutionary processes and ecological patterns underlie the maintenance of asexual reproduction in natural populations? Although a vast body of literature offers theory to explain the existence of sexual and asexual ...