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Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation.

Jin, C; Shelburne, CP; Li, G; Potts, EN; Riebe, KJ; Sempowski, GD; Foster, WM; ... (8 authors) (J Clin Invest, 2011-03)

Allergic asthma is characterized by airway hyperresponsiveness, inflammation, and a cellular infiltrate dominated by eosinophils. Numerous epidemiological studies have related the exacerbation of allergic asthma with an ...