Now showing items 211-215 of 215
Bioorthogonal Functionalization of Elastin-like Polypeptides
Recombinant technology has given us the powerful ability to imagine and create novel biological entities, from potent therapeutics to functionally active materials. By harnessing nature’s building blocks and reconfiguring ...
Imaging at the Limits: Segmentation Error Bounds and High Resolution Retinal Imaging Systems
The human retina is essential to quality of life and therefore a topic of intense clinical and research interest. The combination of this interest with modern biophotonics has yielded a number of technological and medical ...
Blast-Induced Neurotrauma and the Cavitation Mechanism of Injury
Traumatic brain injuries (TBIs) are a major public health concern and socioeconomic burden worldwide. In recent years, brain injuries in US service personnel have focused attention on TBI affecting the military population ...
An Induced Pluripotent Stem Cell-derived Tissue Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome for Disease Modeling and Drug Testing
Hutchison-Gilford Progeria Syndrome (HGPS) is a rare, accelerated aging disorder caused by nuclear accumulation of progerin, an altered form of the Lamin A gene. The primary causes of death are stroke and cardiovascular ...
Integrating Protein Engineering and Genomics for Cancer Therapy
We have developed a broadly applicable platform that harnesses the power of protein engineering and genetic screening to produce efficacious protein-drug combinations for cancer therapy. For proof-of-concept, we implemented ...