Now showing items 1-2 of 2
Distinct functions of POT1 at telomeres.
(Mol Cell Biol, 2008-09)
The mammalian protein POT1 binds to telomeric single-stranded DNA (ssDNA), protecting chromosome ends from being detected as sites of DNA damage. POT1 is composed of an N-terminal ssDNA-binding domain and a C-terminal protein ...
Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity.
(Dev Cell, 2008-07)
The endoplasmic reticulum stress response, also known as the unfolded protein response (UPR), has been implicated in the normal physiology of immune defense and in several disorders, including diabetes, cancer, ...