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A PK2/Bv8/PROK2 antagonist suppresses tumorigenic processes by inhibiting angiogenesis in glioma and blocking myeloid cell infiltration in pancreatic cancer. 

Curtis, Valerie Forbes (2011)
In many cancer types, infiltration of bone marrow-derived myeloid cells in the tumor microenvironment is often associated with enhanced angiogenesis and tumor progression, resulting in poor prognosis. The polypeptide chemokine ...

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AuthorCurtis, Valerie Forbes (1)Date Issued
2011 (1)
TypeDissertation (1)SubjectAnimals (1)Antineoplastic Agents (1)Carrier Proteins (1)Cell Line, Tumor (1)Cell Movement (1)Cell Transformation, Neoplastic (1)Endothelial Cells (1)Gastrointestinal Hormones (1)Glioma (1)Humans (1)... View MoreDepartmentMolecular Cancer Biology (1)Affiliation of Duke Author(s)Basic Science Departments (1)Clinical Science Departments (1)Duke (1)
Duke Cancer Institute (1)
Institutes and Centers (1)
Pathology (1)
Pharmacology & Cancer Biology (1)School of Medicine (1)
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