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Auxiliary Wnt3A Signaling in Cell Fate Decisions of C3H10T1/2 Mesenchymal Stem Cells
Activation of Wnt signaling pathways is critical to a variety of developmental events across all animal taxa. These highly evolutionarily conserved pathways are also important in the adult organism for maintaining homeostasis ...
The Contributions of Histones H3 and H4 to Gene Regulation in <italic>Saccharomyces cerevisiae</italic>: A Closer Look at Sum1 Repression and Sum1-1 Silencing
Chromatin is composed of DNA, histones, and other proteins and contributes to DNA packaging, controlling gene expression and DNA replication. This work focuses on the contributions of histones H3 and H4 to gene regulation ...
Regulation of CaMKKβ Dependent Signaling Pathways
Ca<super>2+</super>/Calmodulin-dependent protein kinase kinase β(CaMKKβ) is a serine/threonine directed kinase which is activated following increases in intracellular Ca<super>2+</super>. CaMKKβ activates ...
Exploring the Immunogenicity and Therapeutic Applications of Boranophosphate-modified RNA: siRNA and RNA Aptamers
Borane (BH<sub>3<sub>) chemistry offers unique chemical characteristics that enable boranophosphate (BP) oligonucleotides with potential to enhance RNA therapeutic applications such as RNA interference (RNAi) and RNA aptamers. ...