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Topic Modeling for Inferring Brain States from Electroencephalography (EEG) Signals
(2018)
Inferring brain states from EEG signals allows for the management of sleep disorders
and brain diseases by providing an insight into the electrophysiological state of
the brain. We explore the use of topic modeling – which ...
Design, Optimization, and Test Methods for Micro-Electrode-Dot-Array Digital Microfluidic Biochips
(2017)
Digital microfluidic biochips (DMFBs) are revolutionizing many biochemical analysis
procedures, e.g., high-throughput DNA sequencing and point-of-care clinical diagnosis.
However, today's DMFBs suffer from several limitations: ...
Custom Silicon Annular Photodiode Arrays for Spatially Resolved Diffuse Reflectance Spectroscopy
(2016)
Diffuse reflectance spectroscopy (DRS) is a simple, yet powerful technique that has
the potential to offer practical, non-invasive, and cost effective information for
op- tical diagnostics and therapeutics guidance. Any ...
Sparse Sample Detection Using Magnetic Bead Manipulation on a Digital Microfluidic Device
(2016)
This thesis demonstrates a new way to achieve sparse biological sample detection,
which uses magnetic bead manipulation on a digital microfluidic device. Sparse sample
detection was made possible through two steps: sparse ...
Toward Better Representations of Sound with Cochlear Implants
(2015)
This dissertation is about the first substantial restoration of human sense using
a medical intervention. In particular, the development of the modern cochlear implant
(CI) is described, with a focus on sound processors ...
Towards Realizing Virtual Clinical Trials for Optimization and Evaluation of Breast Imaging Systems
(2014)
It is essential that breast cancer be detected at its earliest stages for better prognosis.
Advanced imaging techniques and systems are constantly under development and study
to improve the screening and detection of breast ...
Accelerated Sepsis Diagnosis by Seamless Integration of Nucleic Acid Purification and Detection
(2014)
<bold>Background</bold> The diagnosis of sepsis is challenging because the infection
can be caused by more than 50 species of pathogens that might exist in the bloodstream
in very low concentrations, e.g., less ...
Low Voltage DNA Sequencing Platform Utilizing Picofluidic Electrowetting Devices
(2011)
Digital microfluidics as implemented in electrowetting-on-dielectric (EWD) technology
has been widely used as a platform for miniaturizing the biomedical or biochemical
laboratory on a chip in recent years. DNA pyrosequencing, ...
Improved Visualization and Quantification for Hyperpolarized 129Xe MRI
(2019)
In Pulmonary diseases, such as chronic obstructed pulmonary diseases (COPD), fibrosis,
and asthma, are responsible for substantial health and financial burden in the world.
In 2016, COPD claimed more than 3 million lives, ...