Hepatocellular carcinoma (HCC) lesions are often preceded by liver cirrhosis or Hepatitis C, and patients with these diagnoses are monitored every six months with an ultrasound screening. B-mode ultrasound is an ideal imaging ...

Coronary heart disease contributed to approximately one in four deaths in the United States in 2014, and is caused by a restriction of blood flow to myocardial tissue. Stress echocardiography is a clinical technique used ...

X-ray computed tomography (CT) is one of the most useful diagnostic tools for clinicians, with widespread availability, fast scan times, and low cost. CT imaging can reveal a patient’s anatomy in exquisite detail and is ...

Optical coherence tomography (OCT) is a noninvasive three-dimensional interferometric imaging technique capable of achieving micrometer scale resolution. It is now a standard of care in ophthalmology, where it is used to ...

Hyperpolarized (HP) gas MRI is emerging as a powerful, non-invasive method for imaging lung function. MRI of HP 129Xe and 3He was first introduced in small animals and was soon followed by its clinical implementation. 3He ...

Magnetic resonance imaging is a research and clinical tool that has been applied in a wide variety of sciences. One area of magnetic resonance imaging that has exhibited terrific promise and growth in the past decade is ...

X-ray mammography has been the gold standard for breast imaging for decades, despite the significant limitations posed by the two dimensional (2D) image acquisitions. Difficulty in diagnosing lesions close to the chest wall ...

One of the challenges facing clinical practice today is intra-operative margin detection in breast conserving surgeries (BCS) or lumpectomy procedures. When a surgeon removes a breast tumor from a patient during a BCS ...

This dissertation investigates the use of large coherent ultrasound apertures to improve diagnostic image quality for deep clinical targets. The current generation of ultrasound scanners restrict aperture size and geometry ...

Beamforming of ultrasound signals in the presence of clutter, or partial aperture blockage by an acoustic obstacle can lead to reduced visibility of the structures of interest and diminished diagnostic value of the resulting ...