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Multi-Dimensional Ultrasonic Shear Wave Reconstructions: Improving the Accuracy of Viscoelastic Parameter Estimation
(2018)
Hepatocellular carcinoma (HCC) lesions are often preceded by liver cirrhosis or Hepatitis
C, and patients with these diagnoses are monitored every six months with an ultrasound
screening. B-mode ultrasound is an ideal imaging ...
Efficient Spatial Coherence Estimation for Improved Endocardial Border Visualization in Real-Time
(2017)
Coronary heart disease contributed to approximately one in four deaths in the United
States in 2014, and is caused by a restriction of blood flow to myocardial tissue.
Stress echocardiography is a clinical technique used ...
Functional and Molecular Imaging Using Nanoparticle Contrast Agents for Dual-Energy Computed Tomography
(2017)
X-ray computed tomography (CT) is one of the most useful diagnostic tools for clinicians,
with widespread availability, fast scan times, and low cost. CT imaging can reveal
a patient’s anatomy in exquisite detail and is ...
Development of Swept Source Optical Coherence Tomography and Adaptive Optics Scanning Laser Ophthalmoscopy: Improved Imaging Speed and Handheld Applications
(2016)
Optical coherence tomography (OCT) is a noninvasive three-dimensional interferometric
imaging technique capable of achieving micrometer scale resolution. It is now a standard
of care in ophthalmology, where it is used to ...
Preclinical Hyperpolarized 129Xe MRI: Development, Applications, and Dissemination
(2018)
Hyperpolarized (HP) gas MRI is emerging as a powerful, non-invasive method for imaging
lung function. MRI of HP 129Xe and 3He was first introduced in small animals and was
soon followed by its clinical implementation. 3He ...
Probing Tissue Microstructure Using Susceptibility Contrast Magnetic Resonance Imaging
(2016)
Magnetic resonance imaging is a research and clinical tool that has been applied in
a wide variety of sciences. One area of magnetic resonance imaging that has exhibited
terrific promise and growth in the past decade is ...
Investigation and Development of a Fully 3D Tilt Capable Hybrid SPECT - CT System for Dedicated Breast Imaging
(2015)
X-ray mammography has been the gold standard for breast imaging for decades, despite
the significant limitations posed by the two dimensional (2D) image acquisitions.
Difficulty in diagnosing lesions close to the chest wall ...
X-ray Coherent Scatter Imaging for Intra-operative Margin Detection in Breast Conserving Surgeries
(2015)
One of the challenges facing clinical practice today is intra-operative margin detection
in breast conserving surgeries (BCS) or lumpectomy procedures. When a surgeon removes
a breast tumor from a patient during a BCS ...
Ultrasound Beamforming Methods for Large Coherent Apertures
(2017)
This dissertation investigates the use of large coherent ultrasound apertures to improve
diagnostic image quality for deep clinical targets. The current generation of ultrasound
scanners restrict aperture size and geometry ...
Beamforming of Ultrasound Signals from 1-D and 2-D Arrays under Challenging Imaging Conditions
(2015)
Beamforming of ultrasound signals in the presence of clutter, or partial aperture
blockage by an acoustic obstacle can lead to reduced visibility of the structures
of interest and diminished diagnostic value of the resulting ...