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Using Genomic Tools to Understand Speciation Dynamics in Madagascar's Mouse Lemurs (Order: Primates)
Mouse lemurs (genus Microcebus; Order Primates) are endemic to the island nation of Madagascar. These small, nocturnal primates offer a unique mammalian system ideally suited to study the patterns and processes of speciation, ...
Developmental Regulation in Response to Nutritional Status in Caenorhabditis elegans
Developmental physiology is very sensitive to nutrient availability. For instance, in the nematode C. elegans, newly hatched L1-stage larvae require food to initiate postembryonic development. Despite the essential role ...
How Linkage Disequilibrium and Recombination Shape Genetic Variation Within and Between Species
Meiotic recombination creates genetic diversity by shuffling combinations of alleles across loci, yet alleles at neighboring loci often remain non-randomly associated. This non-random association is known as linkage-dise...
Sociogenetic Structure in Indo-Pacific Bottlenose Dolphins (Tursiops aduncus) in Shark Bay, Western Australia
Kinship plays a fundamental role in the evolution of social systems and is considered a key driver of group living. The quantity and quality of an individual’s social relationships can have significant fitness effects, and ...
Development of a High-Throughput Human iPSC Chondrogenesis Platform and Applications for Arthritis Disease Modeling
The differentiation of human induced pluripotent stem cells (hiPSCs) to prescribed cell fates enables the engineering of patient-specific tissue types, such as hyaline cartilage, for applications in regenerative medicine, ...
Responses to Antifungal and Alkaline pH Stress in Human Fungal Pathogens
The fungal pathogens encounter ever-changing conditions during their pathogenic life cycles, including shifts from the environment to the human host. Fungi have evolved many pathways that allow them to overcome and even ...