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The Contributions of Histones H3 and H4 to Gene Regulation in <italic>Saccharomyces cerevisiae</italic>: A Closer Look at Sum1 Repression and Sum1-1 Silencing
Chromatin is composed of DNA, histones, and other proteins and contributes to DNA packaging, controlling gene expression and DNA replication. This work focuses on the contributions of histones H3 and H4 to gene regulation ...
Structural Dynamics and Novel Biological Function of Topoisomerase 2
Eukaryotic Topoisomerase 2 is an essential enzyme that solves DNA topological problems such as DNA knotting, catenation, and supercoiling. It alters the DNA topology by introducing transient double strand break in one DNA ...
The Evolution of the Deacetylase Sir2 in Yeast
Gene duplication is an important evolutionary tool for fostering diversification and expanding gene families. However, while this concept is well understood and accepted in a theoretical capacity, the particular changes ...