Now showing items 1-2 of 2
Investigatiing the Role of the Wild-Type Ras Isoforms in KRas-driven Cancer
The RAS family is a group of small GTPases that can become constitutively activated by point mutations that are found in about 30% of all cancer patients. There are three well-characterized RAS family members: HRAS, NRAS, ...
Genomic Analysis of Cancer Heterogeneity and Oncogenic Mechanisms
The development of cancer is a process by which an accumulation of genetic changes leads to uncontrolled replication of cells. Since the process of mutation is random, the set of alterations that occur and accumulate during ...