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Control of the orientational order and nonlinear optical response of the "push-pull" chromophore RuPZn via specific incorporation into densely packed monolayer ensembles of an amphiphilic four-helix bundle peptide: characterization of the peptide-chromophore complexes.
Abstract
"Push-pull" chromophores based on extended pi-electron systems have been designed
to exhibit exceptionally large molecular hyperpolarizabilities. We have engineered
an amphiphilic four-helix bundle peptide to vectorially incorporate such hyperpolarizable
chromophores having a metalloporphyrin moiety, with high specificity into the interior
core of the bundle. The amphiphilic exterior of the bundle facilitates the formation
of densely packed monolayer ensembles of the vectorially oriented peptide-chromophore
complexes at the liquid-gas interface. Chemical specificity designed into the ends
of the bundle facilitates the subsequent covalent attachment of these monolayer ensembles
onto the surface of an inorganic substrate. In this article, we describe the structural
characterization of these monolayer ensembles at each stage of their fabrication for
one such peptide-chromophore complex designated as AP0-RuPZn. In the accompanying
article, we describe the characterization of their macroscopic nonlinear optical properties.
Type
Journal articleSubject
Amino Acid SequenceGases
Metalloporphyrins
Models, Molecular
Molecular Sequence Data
Nonlinear Dynamics
Optical Phenomena
Organometallic Compounds
Peptides
Protein Structure, Secondary
Spectrophotometry, Ultraviolet
Water
X-Ray Diffraction
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https://hdl.handle.net/10161/4040Published Version (Please cite this version)
10.1021/ja1010702Publication Info
Krishnan, Venkata; Tronin, Andrey; Strzalka, Joseph; Fry, H Christopher; Therien,
Michael J; & Blasie, J Kent (2010). Control of the orientational order and nonlinear optical response of the "push-pull"
chromophore RuPZn via specific incorporation into densely packed monolayer ensembles
of an amphiphilic four-helix bundle peptide: characterization of the peptide-chromophore
complexes. J Am Chem Soc, 132(32). pp. 11083-11092. 10.1021/ja1010702. Retrieved from https://hdl.handle.net/10161/4040.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Michael J. Therien
William R. Kenan, Jr. Distinguished Professor of Chemistry
Our research involves the synthesis of compounds, supramolecular assemblies, nano-scale
objects, and electronic materials with unusual ground-and excited-state characteristics,
and interrogating these structures using state-of-the-art transient optical, spectroscopic,
photophysical, and electrochemical methods. Over chemical dimensions that span molecules
to materials, we probe experimental and theoretical aspects of charge migration reactions
and ultrafast electron transfer processes. Insights

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