Reductive ligation mediated one-step disulfide formation of S-nitrosothiols.
Repository Usage Stats
A one-step reductive ligation mediated disulfide formation of S-nitrosothiols was developed. This reaction involves the reaction of the S-nitroso group with phosphine-thioesters to form sulfenamide and thiolate intermediates, which then undergo a fast intermolecular disulfide formation to form stable conjugates. This reaction can be used to design new biosensors of S-nitrosated proteins.
Published Version (Please cite this version)10.1021/ol101863s
Publication InfoZhang, J; Li, S; Zhang, D; Wang, H; Whorton, AR; & Xian, M (2010). Reductive ligation mediated one-step disulfide formation of S-nitrosothiols. Org Lett, 12(18). pp. 4208-4211. 10.1021/ol101863s. Retrieved from https://hdl.handle.net/10161/4108.
This is constructed from limited available data and may be imprecise. To cite this article, please review & use the official citation provided by the journal.
More InfoShow full item record