Show simple item record Ho, YP Leong, KW
dc.coverage.spatial England 2011-06-21T17:27:14Z 2010-01
dc.identifier.citation Nanoscale, 2010, 2 (1), pp. 60 - 68
dc.description.abstract Luminescent semiconductor nanocrystals, also known as quantum dots (QDs), have advanced the fields of molecular diagnostics and nanotherapeutics. Much of the initial progress for QDs in biology and medicine has focused on developing new biosensing formats to push the limit of detection sensitivity. Nevertheless, QDs can be more than passive bio-probes or labels for biological imaging and cellular studies. The high surface-to-volume ratio of QDs enables the construction of a "smart" multifunctional nanoplatform, where the QDs serve not only as an imaging agent but also a nanoscaffold catering for therapeutic and diagnostic (theranostic) modalities. This mini review highlights the emerging applications of functionalized QDs as fluorescence contrast agents for imaging or as nanoscale vehicles for delivery of therapeutics, with special attention paid to the promise and challenges towards QD-based theranostics.
dc.format.extent 60 - 68
dc.language eng
dc.language.iso en_US en_US
dc.relation.ispartof Nanoscale
dc.relation.isversionof 10.1039/b9nr00178f
dc.subject Aptamers, Nucleotide
dc.subject Contrast Media
dc.subject Drug Carriers
dc.subject Fluorescence Resonance Energy Transfer
dc.subject Humans
dc.subject Microscopy, Fluorescence
dc.subject Pharmaceutical Preparations
dc.subject Quantum Dots
dc.title Quantum dot-based theranostics.
dc.title.alternative en_US
dc.type Journal Article
dc.description.version Version of Record en_US 2010-1-0 en_US
duke.description.endpage 68 en_US
duke.description.issue 1 en_US
duke.description.startpage 60 en_US
duke.description.volume 2 en_US
dc.relation.journal Nanoscale en_US
pubs.issue 1
pubs.organisational-group /Duke
pubs.organisational-group /Duke/Pratt School of Engineering
pubs.organisational-group /Duke/Pratt School of Engineering/Biomedical Engineering
pubs.publication-status Published
pubs.volume 2
dc.identifier.eissn 2040-3372

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