Show simple item record Weitner, T Budimir, A Kos, I Batinić-Haberle, I Biruš, M
dc.coverage.spatial England 2011-06-21T17:27:17Z 2010-12-28
dc.identifier.citation Dalton Trans, 2010, 39 (48), pp. 11568 - 11576
dc.description.abstract The difference in electrostatics and reduction potentials between manganese ortho-tetrakis(N-ethylpyridinium-2-yl)porphyrin (MnTE-2-PyP) and manganese meta-tetrakis(N-ethylpyridinium-3-yl)porphyrin (MnTE-3-PyP) is a challenging topic, particularly because of the high likelihood for their clinical development. Hence, a detailed study of the protolytic and electrochemical speciation of Mn(II-IV)TE-2-PyP and Mn(II-IV)TE-3-PyP in a broad pH range has been performed using the combined spectrophotometric and potentiometric methods. The results reveal that in aqueous solutions within the pH range ∼2-13 the following species exist: (H(2)O)Mn(II)TE-m-PyP(4+), (HO)Mn(II)TE-m-PyP(3+), (H(2)O)(2)Mn(III)TE-m-PyP(5+), (HO)(H(2)O)Mn(III)TE-m-PyP(4+), (O)(H(2)O)Mn(III)TE-m-PyP(3+), (O)(H(2)O)Mn(IV)TE-m-PyP(4+) and (O)(HO)Mn(IV)TE-m-PyP(3+) (m = 2, 3). All the protolytic equilibrium constants that include the accessible species as well as the thermodynamic parameters for each particular protolytic equilibrium have been determined. The corresponding formal reduction potentials related to the reduction of the above species and the thermodynamic parameters describing the accessible reduction couples were calculated as well.
dc.format.extent 11568 - 11576
dc.language eng
dc.language.iso en_US en_US
dc.relation.ispartof Dalton Trans
dc.relation.isversionof 10.1039/c0dt00585a
dc.subject Coordination Complexes
dc.subject Electrochemical Techniques
dc.subject Hydrogen-Ion Concentration
dc.subject Metalloporphyrins
dc.subject Oxidation-Reduction
dc.subject Potentiometry
dc.subject Spectrophotometry, Ultraviolet
dc.subject Thermodynamics
dc.title Acid-base and electrochemical properties of manganese meso(ortho- and meta-N-ethylpyridyl)porphyrins: potentiometric, spectrophotometric and spectroelectrochemical study of protolytic and redox equilibria.
dc.title.alternative en_US
dc.type Journal Article
dc.description.version Version of Record en_US 2010-00-00 en_US
duke.description.endpage 11576 en_US
duke.description.issue 48 en_US
duke.description.startpage 11568 en_US
duke.description.volume 39 en_US
dc.relation.journal Dalton Transactions en_US
pubs.issue 48
pubs.organisational-group /Duke
pubs.organisational-group /Duke/School of Medicine
pubs.organisational-group /Duke/School of Medicine/Clinical Science Departments
pubs.organisational-group /Duke/School of Medicine/Clinical Science Departments/Radiation Oncology
pubs.organisational-group /Duke/School of Medicine/Institutes and Centers
pubs.organisational-group /Duke/School of Medicine/Institutes and Centers/Duke Cancer Institute
pubs.publication-status Published
pubs.volume 39
dc.identifier.eissn 1477-9234

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