Promoting developmental transcription.
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Animal growth and development depend on the precise control of gene expression at the level of transcription. A central role in the regulation of developmental transcription is attributed to transcription factors that bind DNA enhancer elements, which are often located far from gene transcription start sites. Here, we review recent studies that have uncovered significant regulatory functions in developmental transcription for the TFIID basal transcription factors and for the DNA core promoter elements that are located close to transcription start sites.
Gene Expression Regulation, Developmental
Promoter Regions, Genetic
Transcription Factor TFIID
Transcription Initiation Site
Published Version (Please cite this version)10.1242/dev.035493
Publication InfoOhler, Uwe; & Wassarman, DA (2010). Promoting developmental transcription. Development, 137(1). pp. 15-26. 10.1242/dev.035493. Retrieved from https://hdl.handle.net/10161/4172.
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Adjunct Associate Professor in the Department of Biostatistics and Bioinformatics
Computational Biology of Gene Regulation Sequence Analysis Image Expression Analysis Applied Machine Learning