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Measuring morphological features using light-scattering spectroscopy and Fourier-domain low-coherence interferometry.

dc.contributor.author Robles, FE
dc.contributor.author Wax, A
dc.coverage.spatial United States
dc.date.accessioned 2011-06-21T17:27:42Z
dc.date.issued 2010-02-01
dc.identifier http://www.ncbi.nlm.nih.gov/pubmed/20125721
dc.identifier 195211
dc.identifier.uri http://hdl.handle.net/10161/4226
dc.description.abstract We present measurements of morphological features in a thick turbid sample using light-scattering spectroscopy (LSS) and Fourier-domain low-coherence interferometry (fLCI) by processing with the dual-window (DW) method. A parallel frequency domain optical coherence tomography (OCT) system with a white-light source is used to image a two-layer phantom containing polystyrene beads of diameters 4.00 and 6.98 mum on the top and bottom layers, respectively. The DW method decomposes each OCT A-scan into a time-frequency distribution with simultaneously high spectral and spatial resolution. The spectral information from localized regions in the sample is used to determine scatterer structure. The results show that the two scatterer populations can be differentiated using LSS and fLCI.
dc.language eng
dc.language.iso en_US
dc.relation.ispartof Opt Lett
dc.subject Aluminum Oxide
dc.subject Ethylene Glycol
dc.subject Fourier Analysis
dc.subject Interferometry
dc.subject Light
dc.subject Models, Statistical
dc.subject Nanoparticles
dc.subject Nanotechnology
dc.subject Scattering, Radiation
dc.subject Spectrophotometry
dc.subject Surface Plasmon Resonance
dc.subject Water
dc.title Measuring morphological features using light-scattering spectroscopy and Fourier-domain low-coherence interferometry.
dc.title.alternative
dc.type Journal article
dc.description.version Version of Record
duke.date.pubdate 2010-2-1
duke.description.issue 3
duke.description.volume 35
dc.relation.journal Optics Letters
pubs.author-url http://www.ncbi.nlm.nih.gov/pubmed/20125721
pubs.begin-page 360
pubs.end-page 362
pubs.issue 3
pubs.organisational-group Biomedical Engineering
pubs.organisational-group Duke
pubs.organisational-group Duke Institute for Brain Sciences
pubs.organisational-group Institutes and Provost's Academic Units
pubs.organisational-group Pratt School of Engineering
pubs.organisational-group University Institutes and Centers
pubs.publication-status Published
pubs.volume 35
dc.identifier.eissn 1539-4794


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