Intraoperative spectral domain optical coherence tomography for vitreoretinal surgery.
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We demonstrate in vivo human retinal imaging using an intraoperative microscope-mounted optical coherence tomography system (MMOCT). Our optomechanical design adapts an Oculus Binocular Indirect Ophthalmo Microscope (BIOM3), suspended from a Leica ophthalmic surgical microscope, with spectral domain optical coherence tomography (SD-OCT) scanning and relay optics. The MMOCT enables wide-field noncontact real-time cross-sectional imaging of retinal structure, allowing for SD-OCT augmented intrasurgical microscopy for intraocular visualization. We experimentally quantify the axial and lateral resolution of the MMOCT and demonstrate fundus imaging at a 20Hz frame rate.
Tomography, Optical Coherence
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Michael J. Fitzpatrick Distinguished Professor of Engineering in the Edmund T. Pratt, Jr. School of Engineering
My research centers on the development and application of cutting-edge optical technologies for non-invasive, high-resolution imaging and sensing in living biological tissues. Our laboratory is recognized for foundational contributions to optical coherence-based approaches for in vivo sub-surface microscopic tissue imaging, particularly optical coherence tomography (OCT) which has become a standard of care in ophthalmology and other clinical specialties. The technologies we employ includ
Joseph A.C. Wadsworth Distinguished Professor of Ophthalmology
RESEARCH INTERESTS Dr. Toth specializes in the evaluation and surgical treatment of vitreoretinal diseases in infants, children and adults, and in novel research resulting in the clinical application of optical coherence tomography (OCT) imaging in surgery and at the bedside. Her clinical interests and skills include the surgical treatment of macular diseases (such as, macular hole, epiretinal membrane and vitreomacular traction), retinal detachment, proliferative diabetic ret
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