Fiber-optic interferometric two-dimensional scattering-measurement system.
Abstract
We present a fiber-optic interferometric system for measuring depth-resolved scattering
in two angular dimensions using Fourier-domain low-coherence interferometry. The system
is a unique hybrid of the Michelson and Sagnac interferometer topologies. The collection
arm of the interferometer is scanned in two dimensions to detect angular scattering
from the sample, which can then be analyzed to determine the structure of the scatterers.
A key feature of the system is the full control of polarization of both the illumination
and the collection fields, allowing for polarization-sensitive detection, which is
essential for two-dimensional angular measurements. System performance is demonstrated
using a double-layer microsphere phantom. Experimental data from samples with different
sizes and acquired with different polarizations show excellent agreement with Mie
theory, producing structural measurements with subwavelength accuracy.
Type
Journal articlePermalink
https://hdl.handle.net/10161/4231Collections
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Show full item recordScholars@Duke
Adam P. Wax
Professor of Biomedical Engineering
Dr. Wax's research interests include optical spectroscopy for early cancer detection,
novel microscopy and
interferometry techniques.
The study of intact, living cells with optical spectroscopy offers the opportunity
to observe cellular structure, organization and dynamics in a way that is not possible
with traditional methods. We have developed a set of novel spectroscopic techniques
for measuring spatial, temporal and refractive structure on sub-hertz and sub-wavelength
scales based

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