Automatic segmentation of seven retinal layers in SDOCT images congruent with expert manual segmentation.
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Segmentation of anatomical and pathological structures in ophthalmic images is crucial for the diagnosis and study of ocular diseases. However, manual segmentation is often a time-consuming and subjective process. This paper presents an automatic approach for segmenting retinal layers in Spectral Domain Optical Coherence Tomography images using graph theory and dynamic programming. Results show that this method accurately segments eight retinal layer boundaries in normal adult eyes more closely to an expert grader as compared to a second expert grader.
Automatic Data Processing
Diagnostic Techniques, Ophthalmological
Image Processing, Computer-Assisted
Optics and Photonics
Tomography, Optical Coherence
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Professor in the Department of Biomedical Engineering
I am the director of the Vision and Image Processing (VIP) Laboratory. Along with my colleagues, we investigate how to improve early diagnostic methods and find new imaging biomarkers of ocular and neurological diseases in adults (e.g. age-related macular degeneration, diabetic retinopathy, Glaucoma, Alzheimer) and children (e.g. retinopathy or prematurity). We also develop automatic artificial intelligence machine learning and deep learning algorithms to detect/segment/quantify anatomical/patho
Joseph A. Izatt
Michael J. Fitzpatrick Distinguished Professor of Engineering
My research centers on the development and application of cutting-edge optical technologies for non-invasive, high-resolution imaging and sensing in living biological tissues. Our laboratory is recognized for foundational contributions to optical coherence-based approaches for in vivo sub-surface microscopic tissue imaging, particularly optical coherence tomography (OCT) which has become a standard of care in ophthalmology and other clinical specialties. The technologies we employ includ
Cynthia Ann Toth
Joseph A.C. Wadsworth Distinguished Professor of Ophthalmology
RESEARCH INTERESTS Dr. Toth specializes in the evaluation and surgical treatment of vitreoretinal diseases in infants, children and adults, and in novel research resulting in the clinical application of optical coherence tomography (OCT) imaging in surgery and at the bedside. Her clinical interests and skills include the surgical treatment of macular diseases (such as, macular hole, epiretinal membrane and vitreomacular traction), retinal detachment, proliferative diabetic ret
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