Five questions about viruses and microRNAs.
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Published Version (Please cite this version)10.1371/journal.ppat.1000787
Publication InfoCullen, Bryan R (2010). Five questions about viruses and microRNAs. PLoS Pathog, 6(2). pp. e1000787. 10.1371/journal.ppat.1000787. Retrieved from https://hdl.handle.net/10161/4594.
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James B. Duke Distinguished Professor of Molecular Genetics and Microbiology
My laboratory has for sometime been interested in understanding the molecular biology of the replication cycle of the pathogenic retrovirus HIV-1. Because HIV-1 gene expression is primarily regulated by specific RNA:protein interactions, my laboratory has also become interested in the more general area of RNA sequence mediated gene regulation, including nuclear mRNA export and the phenomenon of RNA interference. In the past, my laboratory has worked extensively on Tat, the trans