Engineering Exquisite Nanoscale Behavior with DNA
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Self-assembly is a pervasive natural phenomenon that gives rise to complex structures and functions. It describes processes in which a disordered system of components form organized structures as a consequence of specific, local interactions among the components themselves, without any external direction. Biological self-assembled systems, evolved over billions of years, are more intricate, more energy efficient and more functional than anything researchers have currently achieved at the nanoscale. A challenge for human designed physical self-assembled systems is to catch up with mother nature. I argue through examples that DNA is an apt material to meet this challenge. This work presents:
1. 3D self-assembled DNA nanostructures.
2. Illustrations of the simplicity and power of toehold-mediated strand displacement interactions.
3. Algorithmic constructs in the tile assembly model.
CitationGopalkrishnan, Nikhil (2012). Engineering Exquisite Nanoscale Behavior with DNA. Dissertation, Duke University. Retrieved from http://hdl.handle.net/10161/5771.
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This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.
Rights for Collection: Duke Dissertations