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    Catecholamines, cardiac beta-adrenergic receptors, and heart failure.

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    Date
    2000-04-11
    Authors
    Koch, Walter J
    Lefkowitz, Robert J
    Rockman, Howard A
    Repository Usage Stats
    240
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    230
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    Type
    Journal article
    Subject
    Animals
    Cardiac Output, Low
    Catecholamines
    Humans
    Myocardium
    Receptors, Adrenergic, beta
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    http://hdl.handle.net/10161/5909
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    Scholars@Duke

    Lefkowitz

    Robert J. Lefkowitz

    James B. Duke Professor of Medicine
    The focus of work in this laboratory is on the elucidation of the molecular properties and regulatory mechanisms controlling the function of G protein-coupled receptors. As model systems we utilize the so called adrenergic receptors for adrenaline and related molecules. The goal is to learn the general principles of signal transduction from the outside to the inside of the cell which are involved in systems as diverse as sensory perception, neuro- transmitter and hormonal signaling. Stud
    Rockman

    Howard Allan Rockman

    Edward S. Orgain Professor of Cardiology, in the School of Medicine
    Rockman Lab: Molecular Mechanisms of Hypertrophy and Heart Failure Overall Research Direction: The major focus of this laboratory is to understand the molecular mechanisms of hypertrophy and heart failure. My laboratory uses a strategy that combines state of the art molecular techniques to generate transgenic and gene targeted mouse models, combined with sophisticated physiologic measures of in vivo cardiac function. In this manner, candidate molecules are either selectively
    Alphabetical list of authors with Scholars@Duke profiles.
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