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Risk factors for and estimated incidence of community-associated Clostridium difficile infection, North Carolina, USA.

dc.contributor.author Benoit, SR
dc.contributor.author Engel, J
dc.contributor.author Evans, Sharon E
dc.contributor.author Frederick, J
dc.contributor.author Kutty, PK
dc.contributor.author McDonald, LC
dc.contributor.author Naggie, Susanna
dc.contributor.author Seña, AC
dc.contributor.author Woods, Christopher Wildrick
dc.coverage.spatial United States
dc.date.accessioned 2013-03-06T18:22:09Z
dc.date.issued 2010-02
dc.identifier https://www.ncbi.nlm.nih.gov/pubmed/20113547
dc.identifier.uri https://hdl.handle.net/10161/6345
dc.description.abstract We determined estimated incidence of and risk factors for community-associated Clostridium difficile infection (CA-CDI) among patients treated at 6 North Carolina hospitals. CA-CDI case-patients were defined as adults (>18 years of age) with a positive stool test result for C. difficile toxin and no hospitalization within the prior 8 weeks. CA-CDI incidence was 21 and 46 per 100,000 person-years in Veterans Affairs (VA) outpatients and Durham County populations, respectively. VA case-patients were more likely than controls to have received antimicrobial drugs (adjusted odds ratio [aOR] 17.8, 95% confidence interval [CI] 6.6-48] and to have had a recent outpatient visit (aOR 5.1, 95% CI 1.5-17.9). County case-patients were more likely than controls to have received antimicrobial drugs (aOR 9.1, 95% CI 2.9-28.9), to have gastroesophageal reflux disease (aOR 11.2, 95% CI 1.9-64.2), and to have cardiac failure (aOR 3.8, 95% CI 1.1-13.7). Risk factors for CA-CDI overlap with those for healthcare-associated infection.
dc.language eng
dc.relation.ispartof Emerg Infect Dis
dc.relation.isversionof 10.3201/eid1602.090953
dc.subject Adult
dc.subject Age Distribution
dc.subject Aged
dc.subject Aged, 80 and over
dc.subject Bacterial Proteins
dc.subject Bacterial Toxins
dc.subject Case-Control Studies
dc.subject Clostridium Infections
dc.subject Community-Acquired Infections
dc.subject Dysentery
dc.subject Enterotoxins
dc.subject Feces
dc.subject Female
dc.subject Humans
dc.subject Incidence
dc.subject Male
dc.subject Middle Aged
dc.subject North Carolina
dc.subject Odds Ratio
dc.subject Prejudice
dc.subject Risk Factors
dc.subject Veterans
dc.subject Young Adult
dc.title Risk factors for and estimated incidence of community-associated Clostridium difficile infection, North Carolina, USA.
dc.type Journal article
duke.description.issue 2
duke.description.volume 16
dc.relation.journal Emerging Infectious Diseases
pubs.author-url https://www.ncbi.nlm.nih.gov/pubmed/20113547
pubs.begin-page 197
pubs.end-page 204
pubs.issue 2
pubs.organisational-group Clinical Science Departments
pubs.organisational-group Duke
pubs.organisational-group Duke Clinical Research Institute
pubs.organisational-group Institutes and Centers
pubs.organisational-group Medicine
pubs.organisational-group Medicine, Infectious Diseases
pubs.organisational-group Pathology
pubs.organisational-group School of Medicine
pubs.publication-status Published
pubs.volume 16
dc.identifier.eissn 1080-6059


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