Resolving response, decision, and strategic control: evidence for a functional topography in dorsomedial prefrontal cortex.
Abstract
The dorsomedial prefrontal cortex (DMPFC) plays a central role in aspects of cognitive
control and decision making. Here, we provide evidence for an anterior-to-posterior
topography within the DMPFC using tasks that evoke three distinct forms of control
demands--response, decision, and strategic--each of which could be mapped onto independent
behavioral data. Specifically, we identify three spatially distinct regions within
the DMPFC: a posterior region associated with control demands evoked by multiple incompatible
responses, a middle region associated with control demands evoked by the relative
desirability of decision options, and an anterior region that predicts control demands
related to deviations from an individual's preferred decision-making strategy. These
results provide new insight into the functional organization of DMPFC and suggest
how recent controversies about its role in complex decision making and response mapping
can be reconciled.
Type
Journal articleSubject
Brain MappingCognition
Decision Making
Female
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Male
Neural Pathways
Neuropsychological Tests
Oxygen
Photic Stimulation
Predictive Value of Tests
Prefrontal Cortex
Problem Solving
Reaction Time
Regression (Psychology)
Young Adult
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https://hdl.handle.net/10161/6928Published Version (Please cite this version)
10.1523/JNEUROSCI.2708-09.2009Publication Info
Venkatraman, Vinod; Rosati, Alexandra G; Taren, Adrienne A; & Huettel, Scott A (2009). Resolving response, decision, and strategic control: evidence for a functional topography
in dorsomedial prefrontal cortex. J Neurosci, 29(42). pp. 13158-13164. 10.1523/JNEUROSCI.2708-09.2009. Retrieved from https://hdl.handle.net/10161/6928.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Scott Huettel
Professor in the Department of Psychology and Neuroscience
Research in my laboratory investigates the brain mechanisms underlying economic and
social decision making; collectively, this research falls into the field of “decision
neuroscience” or "neuroeconomics". My laboratory uses fMRI to probe brain function,
behavioral assays to characterize individual differences, and other physiological
methods (e.g., eye tracking, pharmacological manipulation, genetics) to link brain
and behavior. Concurrent with research on basic processes, my labo

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