Functional imaging of numerical processing in adults and 4-y-old children.
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Adult humans, infants, pre-school children, and non-human animals appear to share a system of approximate numerical processing for non-symbolic stimuli such as arrays of dots or sequences of tones. Behavioral studies of adult humans implicate a link between these non-symbolic numerical abilities and symbolic numerical processing (e.g., similar distance effects in accuracy and reaction-time for arrays of dots and Arabic numerals). However, neuroimaging studies have remained inconclusive on the neural basis of this link. The intraparietal sulcus (IPS) is known to respond selectively to symbolic numerical stimuli such as Arabic numerals. Recent studies, however, have arrived at conflicting conclusions regarding the role of the IPS in processing non-symbolic, numerosity arrays in adulthood, and very little is known about the brain basis of numerical processing early in development. Addressing the question of whether there is an early-developing neural basis for abstract numerical processing is essential for understanding the cognitive origins of our uniquely human capacity for math and science. Using functional magnetic resonance imaging (fMRI) at 4-Tesla and an event-related fMRI adaptation paradigm, we found that adults showed a greater IPS response to visual arrays that deviated from standard stimuli in their number of elements, than to stimuli that deviated in local element shape. These results support previous claims that there is a neurophysiological link between non-symbolic and symbolic numerical processing in adulthood. In parallel, we tested 4-y-old children with the same fMRI adaptation paradigm as adults to determine whether the neural locus of non-symbolic numerical activity in adults shows continuity in function over development. We found that the IPS responded to numerical deviants similarly in 4-y-old children and adults. To our knowledge, this is the first evidence that the neural locus of adult numerical cognition takes form early in development, prior to sophisticated symbolic numerical experience. More broadly, this is also, to our knowledge, the first cognitive fMRI study to test healthy children as young as 4 y, providing new insights into the neurophysiology of human cognitive development.
Published Version (Please cite this version)10.1371/journal.pbio.0040125
Publication InfoCantlon, Jessica F; Brannon, Elizabeth M; Carter, Elizabeth J; & Pelphrey, Kevin A (2006). Functional imaging of numerical processing in adults and 4-y-old children. PLoS biology, 4(5). 10.1371/journal.pbio.0040125. Retrieved from https://hdl.handle.net/10161/6960.
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Professor in the Department of Psychology and Neuroscience
Dr. Brannon's research program examines the evolution and development of quantitative cognition. She studies how number, time, and spatial extent are represented by adult humans, infants, young children and nonhuman animals without language. With her many collaborators at Duke she applies behavioral techniques, event-related potentials, functional magnetic resonance imaging, and single-unit physiology to explore the cognitive and neural underpinnings of numerical cognition in nonhuman primates
This author no longer has a Scholars@Duke profile, so the information shown here reflects their Duke status at the time this item was deposited.