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dc.contributor.author Güzeldere, G
dc.contributor.author Mack, PB
dc.contributor.author McCarthy, G
dc.contributor.author Pelphrey, Kevin A
dc.contributor.author Song, A
dc.coverage.spatial England
dc.date.accessioned 2013-04-29T19:27:53Z
dc.date.issued 2003-05-23
dc.identifier http://www.ncbi.nlm.nih.gov/pubmed/12802182
dc.identifier.issn 0959-4965
dc.identifier.uri http://hdl.handle.net/10161/6962
dc.description.abstract Using fMRI techniques sensitive to blood oxygen-level dependent (BOLD) contrast, we measured brain activity in participants (n=8) as they viewed images of faces presented periodically within a continuously changing montage of common objects. Consistent with prior studies, we identified regions of ventral extrastriate cortex, primarily in the fusiform and inferior temporal gyri and nearby cortex, that were activated by faces as measured by an increase in BOLD signal. In addition, we made the novel observation that faces deactivated other areas of ventral extrastriate cortex, primarily in the lingual and parahippocampal gyri and medial to activations. These deactivated regions, identified by a decrease in BOLD signal, may reflect populations of neurons that decrease their activity when faces appear, possibly as a consequence of category-specific inhibition.
dc.language eng
dc.relation.ispartof Neuroreport
dc.relation.isversionof 10.1097/01.wnr.0000074345.81633.ad
dc.subject Adult
dc.subject Brain
dc.subject Brain Mapping
dc.subject Face
dc.subject Female
dc.subject Humans
dc.subject Magnetic Resonance Imaging
dc.subject Male
dc.subject Photic Stimulation
dc.title Faces evoke spatially differentiated patterns of BOLD activation and deactivation.
dc.type Journal article
pubs.author-url http://www.ncbi.nlm.nih.gov/pubmed/12802182
pubs.begin-page 955
pubs.end-page 959
pubs.issue 7
pubs.organisational-group Basic Science Departments
pubs.organisational-group Biomedical Engineering
pubs.organisational-group Clinical Science Departments
pubs.organisational-group Duke
pubs.organisational-group Duke Cancer Institute
pubs.organisational-group Duke Institute for Brain Sciences
pubs.organisational-group Institutes and Centers
pubs.organisational-group Institutes and Provost's Academic Units
pubs.organisational-group Neurobiology
pubs.organisational-group Pratt School of Engineering
pubs.organisational-group Psychiatry & Behavioral Sciences
pubs.organisational-group Radiology
pubs.organisational-group School of Medicine
pubs.organisational-group University Institutes and Centers
pubs.publication-status Published
pubs.volume 14


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