Show simple item record

dc.contributor.author Pelphrey, KA
dc.contributor.author Mack, PB
dc.contributor.author Song, A
dc.contributor.author Güzeldere, G
dc.contributor.author McCarthy, G
dc.coverage.spatial England
dc.date.accessioned 2013-04-29T19:27:53Z
dc.date.issued 2003-05-23
dc.identifier http://www.ncbi.nlm.nih.gov/pubmed/12802182
dc.identifier.citation Neuroreport, 2003, 14 (7), pp. 955 - 959
dc.identifier.issn 0959-4965
dc.identifier.uri http://hdl.handle.net/10161/6962
dc.description.abstract Using fMRI techniques sensitive to blood oxygen-level dependent (BOLD) contrast, we measured brain activity in participants (n=8) as they viewed images of faces presented periodically within a continuously changing montage of common objects. Consistent with prior studies, we identified regions of ventral extrastriate cortex, primarily in the fusiform and inferior temporal gyri and nearby cortex, that were activated by faces as measured by an increase in BOLD signal. In addition, we made the novel observation that faces deactivated other areas of ventral extrastriate cortex, primarily in the lingual and parahippocampal gyri and medial to activations. These deactivated regions, identified by a decrease in BOLD signal, may reflect populations of neurons that decrease their activity when faces appear, possibly as a consequence of category-specific inhibition.
dc.format.extent 955 - 959
dc.language eng
dc.relation.ispartof Neuroreport
dc.relation.isversionof 10.1097/01.wnr.0000074345.81633.ad
dc.subject Adult
dc.subject Brain
dc.subject Brain Mapping
dc.subject Face
dc.subject Female
dc.subject Humans
dc.subject Magnetic Resonance Imaging
dc.subject Male
dc.subject Photic Stimulation
dc.title Faces evoke spatially differentiated patterns of BOLD activation and deactivation.
dc.type Journal Article
pubs.author-url http://www.ncbi.nlm.nih.gov/pubmed/12802182
pubs.issue 7
pubs.organisational-group /Duke
pubs.organisational-group /Duke/Institutes and Provost's Academic Units
pubs.organisational-group /Duke/Institutes and Provost's Academic Units/University Institutes and Centers
pubs.organisational-group /Duke/Institutes and Provost's Academic Units/University Institutes and Centers/Duke Institute for Brain Sciences
pubs.organisational-group /Duke/Pratt School of Engineering
pubs.organisational-group /Duke/Pratt School of Engineering/Biomedical Engineering
pubs.organisational-group /Duke/School of Medicine
pubs.organisational-group /Duke/School of Medicine/Basic Science Departments
pubs.organisational-group /Duke/School of Medicine/Basic Science Departments/Neurobiology
pubs.organisational-group /Duke/School of Medicine/Clinical Science Departments
pubs.organisational-group /Duke/School of Medicine/Clinical Science Departments/Psychiatry & Behavioral Sciences
pubs.organisational-group /Duke/School of Medicine/Clinical Science Departments/Radiology
pubs.organisational-group /Duke/School of Medicine/Institutes and Centers
pubs.organisational-group /Duke/School of Medicine/Institutes and Centers/Duke Cancer Institute
pubs.publication-status Published
pubs.volume 14

Files in this item

This item appears in the following Collection(s)

Show simple item record