Anti–β1-adrenergic receptor antibodies and heart failure: causation, not just correlation
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https://hdl.handle.net/10161/7795Published Version (Please cite this version)
10.1172/JCI200421748Publication Info
Freedman, NJ; & Lefkowitz, Robert J (2004). Anti–β1-adrenergic receptor antibodies and heart failure: causation, not just correlation.
Journal of Clinical Investigation, 113(10). pp. 1379-1382. 10.1172/JCI200421748. Retrieved from https://hdl.handle.net/10161/7795.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Robert J. Lefkowitz
James B. Duke Distinguished Professor of Medicine
The focus of work in this laboratory is on the elucidation of the molecular properties
and regulatory mechanisms controlling the function of G protein-coupled receptors.
As model systems we utilize the so called adrenergic receptors for adrenaline and
related molecules. The goal is to learn the general principles of signal transduction
from the outside to the inside of the cell which are involved in systems as diverse
as sensory perception, neuro- transmitter and hormonal signaling. Stud

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